Targeted drug delivery with polymers and magnetic nanoparticles: covalent and noncovalent approaches, release control, and clinical studies

K Ulbrich, K Hola, V Subr, A Bakandritsos… - Chemical …, 2016 - ACS Publications
Targeted delivery combined with controlled drug release has a pivotal role in the future of
personalized medicine. This review covers the principles, advantages, and drawbacks of …

Current state of breast cancer diagnosis, treatment, and theranostics

A Bhushan, A Gonsalves, JU Menon - Pharmaceutics, 2021 - mdpi.com
Breast cancer is one of the leading causes of cancer-related morbidity and mortality in
women worldwide. Early diagnosis and effective treatment of all types of cancers are crucial …

Applications of magnetic nanoparticles in biomedicine

QA Pankhurst, J Connolly, SK Jones… - Journal of physics D …, 2003 - iopscience.iop.org
The physical principles underlying some current biomedical applications of magnetic
nanoparticles are reviewed. Starting from well-known basic concepts, and drawing on …

[HTML][HTML] Noninvasive detection of clinically occult lymph-node metastases in prostate cancer

MG Harisinghani, J Barentsz, PF Hahn… - … England Journal of …, 2003 - Mass Medical Soc
Background Accurate detection of lymph-node metastases in prostate cancer is an essential
component of the approach to treatment. We investigated whether highly lymphotropic …

Magnetic iron oxide nanoparticles as drug carriers: clinical relevance

K El-Boubbou - Nanomedicine, 2018 - Taylor & Francis
Significant preclinical and clinical research has explored the use of magnetic iron oxide
nanoparticles (MNPs) for medical theranostics. Herein, we provide an overview of the …

Superparamagnetic colloids: controlled synthesis and niche applications

U Jeong, X Teng, Y Wang, H Yang, Y Xia - Advanced Materials, 2007 - Wiley Online Library
The aim of this article is to provide a comprehensive review of current research activities that
center on superparamagnetic colloids. We begin with an overview of synthetic strategies that …

Emerging implications of nanotechnology on cancer diagnostics and therapeutics

AG Cuenca, H Jiang, SN Hochwald, M Delano… - Cancer, 2006 - Wiley Online Library
Nanotechnology is multidisciplinary field that involves the design and engineering of
objects< 500 nanometers (nm) in size. The National Cancer Institute has recognized that …

Current Status of Breast MR Imaging Part 2. Clinical Applications1

CK Kuhl - Radiology, 2007 - pubs.rsna.org
Magnetic resonance (MR) imaging is emerging as the most sensitive modality that is
currently available for the detection of primary or recurrent breast cancer. Although this …

Is sentinel lymph node biopsy a viable alternative to complete axillary dissection following neoadjuvant chemotherapy in women with node-positive breast cancer at …

HEH Chehade, H Headon, O El Tokhy… - The American Journal of …, 2016 - Elsevier
BACKGROUND The use of sentinel lymph node biopsy (SLNB) following neoadjuvant
chemotherapy (NAC) in patients presenting with clinically positive lymph nodes remains …

Near-infrared gold nanocages as a new class of tracers for photoacoustic sentinel lymph node mapping on a rat model

KH Song, C Kim, CM Cobley, Y Xia, LV Wang - Nano letters, 2009 - ACS Publications
This work demonstrated the use of Au nanocages as a new class of lymph node tracers for
noninvasive photoacoustic (PA) imaging of a sentinel lymph node (SLN). Current SLN …