Nanotechnology's frontier in combatting infectious and inflammatory diseases: prevention and treatment

Y Huang, X Guo, Y Wu, X Chen, L Feng, N Xie… - … and Targeted Therapy, 2024 - nature.com
Inflammation-associated diseases encompass a range of infectious diseases and non-
infectious inflammatory diseases, which continuously pose one of the most serious threats to …

[HTML][HTML] Block copolymer micelles as ocular drug delivery systems

AA Assiri, K Glover, D Mishra, D Waite, LK Vora… - Drug Discovery …, 2024 - Elsevier
Highlights•Amphiphilic polymers self-assemble into block copolymer micelles in
solution.•Polymeric micelles have longer and better contact with the ocular …

[HTML][HTML] Parafilm® M and Strat-M® as skin simulants in in vitro permeation of dissolving microarray patches loaded with proteins

QK Anjani, ADC Nainggolan, H Li, A Miatmoko… - International Journal of …, 2024 - Elsevier
In vitro permeation studies play a crucial role in early formulation optimisation before
extensive animal model investigations. Biological membranes are typically used in these …

3D Printing of Biodegradable Polymeric Microneedles for Transdermal Drug Delivery Applications

FK Aldawood, SK Parupelli, A Andar, S Desai - Pharmaceutics, 2024 - mdpi.com
Microneedle (MN) technology is an optimal choice for the delivery of drugs via the
transdermal route, with a minimally invasive procedure. MN applications are varied from …

Rolling Stone Gathers Moss: Rolling Microneedles Generate Meta Microfluidic Microneedles (MMM)

Q Zhou, K Dong, M Wei, B He… - Advanced Functional …, 2024 - Wiley Online Library
Microfluidic chips play crucial roles while lack satisfactory controllability and comprehensive
functionality. Inspired by biological systems, this study proposes a method utilizing rolling …

[HTML][HTML] Long-acting transdermal drug delivery formulations: Current developments and innovative pharmaceutical approaches

T Karve, A Dandekar, V Agrahari, MM Peet… - Advanced Drug Delivery …, 2024 - Elsevier
Transdermal administration remains an active research and development area as an
alternative route for long-acting drug delivery. It avoids major drawbacks of conventional oral …

[HTML][HTML] Hollow microneedles for ocular drug delivery

S Gade, K Glover, D Mishra, S Sharma, O Guy… - Journal of Controlled …, 2024 - Elsevier
Microneedles (MNs) are micron-sized needles, typically< 2 mm in length, arranged either as
an array or as single needle. These MNs offer a minimally invasive approach to ocular drug …

Calcipotriol Nanosuspension-Loaded Trilayer Dissolving Microneedle Patches for the Treatment of Psoriasis: In Vitro Delivery and In Vivo Antipsoriatic Activity Studies

X Dai, AD Permana, M Li, Habibie… - Molecular …, 2024 - ACS Publications
Psoriasis, affecting 2–3% of the global population, is a chronic inflammatory skin condition
without a definitive cure. Current treatments focus on managing symptoms. Recognizing the …

Anti-inflammatory PEGylated bilirubin microneedle patch for diabetes treatment

Y Kuang, F Xue, Z Dai, Y Zhu, Q Liu, H Chen - Applied Materials Today, 2024 - Elsevier
The long-term hyperglycemic environment could easily cause chronic metabolic
inflammation with physiological disorders, exacerbate inflammatory cytokine storms …

Theory of nanostructured sensors integrated in/on microneedles for diagnostics and therapy

M Fratus, MA Alam - Biosensors and Bioelectronics, 2024 - Elsevier
Efficient real-time diagnostics and on-demand drug delivery are essential components in
modern healthcare, especially for managing chronic diseases. The lack of a rapid and …