Nanoparticle-guided brain drug delivery: Expanding the therapeutic approach to neurodegenerative diseases

C Riccardi, F Napolitano, D Montesarchio, S Sampaolo… - Pharmaceutics, 2021 - mdpi.com
Neurodegenerative diseases (NDs) represent a heterogeneous group of aging-related
disorders featured by progressive impairment of motor and/or cognitive functions, often …

[HTML][HTML] Functionalization strategies of polymeric nanoparticles for drug delivery in Alzheimer's disease: Current trends and future perspectives

L La Barbera, E Mauri, M D'Amelio… - Frontiers in Neuroscience, 2022 - frontiersin.org
Alzheimer's disease (AD), the most common form of dementia, is a progressive and
multifactorial neurodegenerative disorder whose primary causes are mostly unknown. Due …

Biomaterials in the treatment of Parkinson's disease

UM Krishnan - Neurochemistry International, 2021 - Elsevier
Parkinson's disease is a neurodegenerative disease, the treatment of which is mainly
centred around supplementation of dopamine. Additional targets have been identified and …

α‐synuclein abnormalities trigger focal tau pathology, spreading to various brain areas in Parkinson disease

F Hadi, H Akrami, M Totonchi… - Journal of …, 2021 - Wiley Online Library
Parkinson disease (PD) is the second most common neurodegenerative disorder, whose
prevalence is 2~ 3% in the population over 65. α‐Synuclein aggregation is the major …

[HTML][HTML] Parkinson's disease: A nanotheranostic approach targeting alpha-synuclein aggregation

FLG Zoey, M Palanivel, P Padmanabhan… - Frontiers in Cell and …, 2021 - frontiersin.org
Parkinson's disease (PD) is one of the most common neurodegenerative disorders that is
implicated in aging populations. As numerous developed nations are experiencing …

Poly (butyl cyanoacrylate) nanoparticles-delivered β-nerve growth factor promotes the neurite outgrowth and reduces the mortality in the rat after traumatic brain injury

Y Wang, F Jia, Y Lin - Nanotechnology, 2022 - iopscience.iop.org
Several transport vectors, including nanoparticles, have been reported to be used for the
delivery of therapeutic medicines crossing the impermeable blood-brain barrier (BBB) to …

Biomaterial strategies for restorative therapies in Parkinson's disease

S Mirzaei, K Kulkarni, K Zhou, PJ Crack… - ACS Chemical …, 2021 - ACS Publications
Parkinson's disease (PD) is a progressive neurological disorder, in which dopaminergic
midbrain neurons degenerate, leading to dopamine depletion that is associated with …

Nanotheranostic agents for neurodegenerative diseases

P Padmanabhan, M Palanivel, A Kumar… - Emerging Topics in …, 2020 - portlandpress.com
Neurodegenerative diseases (NDDs), including Alzheimer's disease (AD) and Parkinson's
disease (PD), affect the ageing population worldwide and while severely impairing the …

Antiparkinsonian agents in investigational polymeric micro-and Nano-Systems

N Paccione, M Rahmani, E Barcia, S Negro - Pharmaceutics, 2022 - mdpi.com
Parkinson's disease (PD) is a devastating neurodegenerative disease characterized by
progressive destruction of dopaminergic tissue in the central nervous system (CNS). To …

Oxidized alginate dopamine conjugate: A study to gain insight into cell/particle interactions

A Trapani, F Corbo, E Stefàno, L Capobianco… - Journal of Functional …, 2022 - mdpi.com
Background: We had previously synthetized a macromolecular prodrug consisting of
oxidized Alginate and dopamine (AlgOx-Da) for a potential application in Parkinson disease …