The human skin microbiome in selected cutaneous diseases

S Carmona-Cruz, L Orozco-Covarrubias… - Frontiers in cellular …, 2022 - frontiersin.org
The human skin harbors a wide variety of microbes that, together with their genetic
information and host interactions, form the human skin microbiome. The role of the human …

Microbiome and human aging: probiotic and prebiotic potentials in longevity, skin health and cellular senescence

JL Boyajian, M Ghebretatios, S Schaly, P Islam… - Nutrients, 2021 - mdpi.com
The role of the microbiome in human aging is important: the microbiome directly impacts
aging through the gastrointestinal system. However, the microbial impact on skin has yet to …

[HTML][HTML] Anatomy promotes neutral coexistence of strains in the human skin microbiome

A Conwill, AC Kuan, R Damerla, AJ Poret, JS Baker… - Cell Host & Microbe, 2022 - cell.com
What enables strains of the same species to coexist in a microbiome? Here, we investigate
whether host anatomy can explain strain co-residence of Cutibacterium acnes, the most …

Living in your skin: microbes, molecules, and mechanisms

MH Swaney, LR Kalan - Infection and immunity, 2021 - Am Soc Microbiol
Human skin functions as a physical, chemical, and immune barrier against the external
environment while also providing a protective niche for its resident microbiota, known as the …

Episymbiotic Saccharibacteria suppresses gingival inflammation and bone loss in mice through host bacterial modulation

O Chipashvili, DR Utter, JK Bedree, Y Ma, F Schulte… - Cell host & …, 2021 - cell.com
Saccharibacteria (TM7) are obligate epibionts living on the surface of their host bacteria and
are strongly correlated with dysbiotic microbiomes during periodontitis and other …

From Dysbiosis to Healthy Skin: Major Contributions of Cutibacterium acnes to Skin Homeostasis

M Rozas, A Hart de Ruijter, MJ Fabrega, A Zorgani… - Microorganisms, 2021 - mdpi.com
Cutibacterium acnes is the most abundant bacterium living in human, healthy and sebum-
rich skin sites, such as the face and the back. This bacterium is adapted to this specific …

Skin dysbiosis and Cutibacterium acnes biofilm in inflammatory acne lesions of adolescents

I Cavallo, F Sivori, M Truglio, F De Maio, F Lucantoni… - Scientific Reports, 2022 - nature.com
Acne vulgaris is a common inflammatory disorder affecting more than 80% of young
adolescents. Cutibacterium acnes plays a role in the pathogenesis of acne lesions, although …

A Janus-Faced Bacterium: Host-Beneficial and -Detrimental Roles of Cutibacterium acnes

H Brüggemann, L Salar-Vidal, HPM Gollnick… - Frontiers in …, 2021 - frontiersin.org
The bacterial species Cutibacterium acnes (formerly known as Propionibacterium acnes) is
tightly associated with humans. It is the dominant bacterium in sebaceous regions of the …

Environmental air pollutants affecting skin functions with systemic implications

G Bocheva, RM Slominski, AT Slominski - International Journal of …, 2023 - mdpi.com
The increase in air pollution worldwide represents an environmental risk factor that has
global implications for the health of humans worldwide. The skin of billions of people is …

Antimicrobial production by perifollicular dermal preadipocytes is essential to the pathophysiology of acne

AM O'Neill, MC Liggins, JS Seidman, TH Do… - Science translational …, 2022 - science.org
Innate immune defense against deep tissue infection by Staphylococcus aureus is
orchestrated by fibroblasts that become antimicrobial when triggered to differentiate into …