Strategic design of intelligent-responsive nanogel carriers for cancer therapy
Owing to the distinctive constituents of tumor tissue from those healthy organs,
nanomedicine strategies show significant potentials in smart drug delivery. Nowadays …
nanomedicine strategies show significant potentials in smart drug delivery. Nowadays …
Poly (disulfide) s: from synthesis to drug delivery
Bioresponsive polymers have been widely used in drug delivery because of their
degradability. For example, poly (disulfide) s with repeating disulfide bonds in the main …
degradability. For example, poly (disulfide) s with repeating disulfide bonds in the main …
Cyclodextrin-containing redox-responsive nanogels: Fabrication of a modular targeted drug delivery system
Among various nanoscale drug delivery systems, biodegradable polymeric nanogels
present a viable platform for targeted cancer therapy. Herein, we report the fabrication of a …
present a viable platform for targeted cancer therapy. Herein, we report the fabrication of a …
Redox-responsive hydrogels for tunable and “On-demand” release of biomacromolecules
R Kilic Boz, D Aydin, S Kocak, B Golba… - Bioconjugate …, 2022 - ACS Publications
In recent years, stimuli-responsive degradation has emerged as a desirable design criterion
for functional hydrogels to tune the release of encapsulated payload as well as ensure …
for functional hydrogels to tune the release of encapsulated payload as well as ensure …
[HTML][HTML] Chemical conjugation strategies for the development of protein-based subunit nanovaccines
The production of subunit nanovaccines relies heavily on the development of a vaccine
delivery system that is safe and efficient at delivering antigens to the target site …
delivery system that is safe and efficient at delivering antigens to the target site …
Redox-responsive nanogels for drug-delivery: thiol–maleimide and thiol–disulfide exchange chemistry as orthogonal tools for fabrication and degradation
Stimuli-responsive, readily functionalizable, and degradable nanogels have great potential
in targeted drug delivery applications. While crosslinked polymeric nanoparticles such as …
in targeted drug delivery applications. While crosslinked polymeric nanoparticles such as …
Upper critical solution temperature polymeric drug carriers
M Le, W Huang, KF Chen, C Lin, L Cai, H Zhang… - Chemical Engineering …, 2022 - Elsevier
Stimuli-responsive polymers are widely used as drug carriers in therapeutic applications.
Upper critical solution temperature (UCST) polymeric carriers undergo a phase transition …
Upper critical solution temperature (UCST) polymeric carriers undergo a phase transition …
Fast-Forming Dissolvable Redox-Responsive Hydrogels: Exploiting the Orthogonality of Thiol–Maleimide and Thiol–Disulfide Exchange Chemistry
Fast-forming yet easily dissolvable hydrogels (HGs) have potential applications in wound
healing, burn incidences, and delivery of therapeutic agents. Herein, a combination of a thiol …
healing, burn incidences, and delivery of therapeutic agents. Herein, a combination of a thiol …
Star polymer networks: a toolbox for cross-linked polymers with controlled structure
S Nakagawa, N Yoshie - Polymer Chemistry, 2022 - pubs.rsc.org
The synthesis of precisely controlled polymer networks has been a long-cherished dream of
polymer scientists. Traditional random cross-linking strategies often lead to uncontrolled …
polymer scientists. Traditional random cross-linking strategies often lead to uncontrolled …
Tumor cell-surface binding of immune stimulating polymeric glyco-adjuvant via cysteine-reactive pyridyl disulfide promotes antitumor immunity
Immune stimulating agents like Toll-like receptor 7 (TLR7) agonists induce potent antitumor
immunity but are limited in their therapeutic window due to off-target immune activation …
immunity but are limited in their therapeutic window due to off-target immune activation …