Activation of microglia and astrocytes: a roadway to neuroinflammation and Alzheimer's disease
Alzheimer's disease (AD) is a neurodegenerative disease that is of high importance to the
neuroscience world, yet the complex pathogenicity is not fully understood. Inflammation is …
neuroscience world, yet the complex pathogenicity is not fully understood. Inflammation is …
Immune attack: the role of inflammation in Alzheimer disease
The past two decades of research into the pathogenesis of Alzheimer disease (AD) have
been driven largely by the amyloid hypothesis; the neuroinflammation that is associated with …
been driven largely by the amyloid hypothesis; the neuroinflammation that is associated with …
Current research therapeutic strategies for Alzheimer's disease treatment
Alzheimer's disease (AD) currently presents one of the biggest healthcare issues in the
developed countries. There is no effective treatment capable of slowing down disease …
developed countries. There is no effective treatment capable of slowing down disease …
Resveratrol and neuroprotection: an insight into prospective therapeutic approaches against Alzheimer's disease from bench to bedside
Alzheimer's disease (AD) is the most common cause of dementia and cognitive impairment;
yet, there is currently no treatment. A buildup of Aβ, tau protein phosphorylation, oxidative …
yet, there is currently no treatment. A buildup of Aβ, tau protein phosphorylation, oxidative …
Towards modern-age advanced sensors for the management of neurodegenerative disorders: current status, challenges and prospects
A Gautam - ECS Sensors Plus, 2022 - iopscience.iop.org
Neurodegenerative diseases (NDD) are progressive degenerative disorders of the
neurological system with significant social impact worldwide. Their detection at the initial …
neurological system with significant social impact worldwide. Their detection at the initial …
Polyphenols as potential metal chelation compounds against Alzheimer's disease
J Lakey-Beitia, AM Burillo, G La Penna… - Journal of …, 2021 - content.iospress.com
Alzheimer's disease (AD) is the most common neurodegenerative disease affecting more
than 50 million people worldwide. The pathology of this multifactorial disease is primarily …
than 50 million people worldwide. The pathology of this multifactorial disease is primarily …
[HTML][HTML] Double-blind, placebo-controlled, proof-of-concept trial of bexarotene in moderate Alzheimer's disease
Background We assessed the impact of retinoid X receptor (RXR) agonist bexarotene on
brain amyloid measured by amyloid imaging in patients with Alzheimer's disease (AD) in a …
brain amyloid measured by amyloid imaging in patients with Alzheimer's disease (AD) in a …
[HTML][HTML] Review of the advances in treatment for Alzheimer disease: strategies for combating β-amyloid protein
Introduction Alzheimer disease (AD) is a major neurodegenerative disorder which
eventually results in total intellectual disability. The high global prevalence and the …
eventually results in total intellectual disability. The high global prevalence and the …
Alzheimer's disease mechanisms and emerging roads to novel therapeutics
C Sala Frigerio, B De Strooper - Annual review of neuroscience, 2016 - annualreviews.org
Ten years of remarkable progress in understanding the fundamental biochemistry of
Alzheimer's disease have been followed by ten years of remarkable and increasing clinical …
Alzheimer's disease have been followed by ten years of remarkable and increasing clinical …
[HTML][HTML] Carotenoids as novel therapeutic molecules against neurodegenerative disorders: Chemistry and molecular docking analysis
Alzheimer's disease (AD) is the most devastating neurodegenerative disorder that affects the
aging population worldwide. Endogenous and exogenous factors are involved in triggering …
aging population worldwide. Endogenous and exogenous factors are involved in triggering …