Strategies for management of patients with, or at risk for, medication-related osteonecrosis of
the jaws (MRONJ)–formerly referred to as bisphosphonate-related osteonecrosis of the jaws …

Angiogenesis, the formation of new blood vessels, is a complex and dynamic process
regulated by various pro-and anti-angiogenic molecules, which plays a crucial role in tumor …

Glioblastoma (GBM) is a devastating type of brain tumor, and current therapeutic treatments,
including surgery, chemotherapy, and radiation, are palliative at best. The design of effective …

Mast cells are hematopoietic cells that reside in virtually all vascularized tissues and that
represent potential sources of a wide variety of biologically active secreted products …

The microenvironment characteristics of solid tumors, renowned as barriers that harshly
impeded many drug-delivery approaches, were precisely studied, investigated, categorized …

Abstract Fibroblast growth factor (FGF) 2, FGF4, FGF7 and FGF20 are representative
paracrine FGFs binding to heparan-sulfate proteoglycan and fibroblast growth factor …

Innate and adaptive immune cells patrol and survey throughout the human body and
sometimes reside in the tumor microenvironment (TME) with a variety of cell types and …

The concept of antiangiogenic therapy in cancer treatment has led to the approval of
different agents, most of them targeting the well known vascular endothelial growth factor …

Angiogenesis is the formation of new blood vessels from pre-existing vessels. It is a highly
regulated process as determined by the interplay between pro-angiogenic and anti …

Epidemiological studies have revealed that high consumption of soy products is associated
with low incidences of hormone-dependent cancers, including breast and prostate cancer …