Aims This first‐in‐human clinical trial of P218, a novel dihydrofolate reductase inhibitor
antimalarial candidate, assessed safety, tolerability, pharmacokinetics and food effects in …

Background Despite a considerable reduction in child mortality, nearly six million children
under the age of five die each year. Millions more are poorly nourished and in many parts of …

Introduction Global progress in reducing malaria has stalled since 2015. Analysis of the
situation is particularly needed in Nigeria, the country with by far the largest share of the …

Background Malaria is among the top causes of mortality and morbidity in Zambia. Efforts to
control, prevent, and eliminate it have been intensified in the past two decades which has …

Background The high burden of malaria and limited funding means there is a necessity to
maximize the allocative efficiency of malaria control programmes. Quantitative tools are …

Background Seasonal malaria chemoprevention (SMC) involves administering antimalarial
drugs at monthly intervals during the high malaria transmission period to children aged 3 to …

In an effort to accelerate progress towards achieving Millennium Development Goal (MDG) 4
and 5, provision of essential reproductive, maternal, newborn and child health (RMNCH) …

Background Seasonal malaria chemoprevention (SMC) is a main intervention to prevent
and reduce childhood malaria. Since 2015, Guinea has implemented SMC targeting …

This report provides a summary of the methods used in the model to simulate a range of
patient management flow charts based on syndromic management plus existing diagnostic …

This document is a PDF generated from the WHO Guidelines for malaria hosted on the
MAGICapp online platform: https://app. magicapp. org/#/guideline/6086. Each time the …