Current status and prospects of clinical treatment of osteosarcoma

ZY Jiang, JB Liu, XF Wang, YS Ma… - Technology in cancer …, 2022 - journals.sagepub.com
Osteosarcoma, one of the common malignant tumors in the skeletal system, originates in
mesenchymal tissue, and the most susceptible area of occurrence is the metaphysis with its …

NLRP3 inflammasome as a potentially new therapeutic target of mesenchymal stem cells and their exosomes in the treatment of inflammatory eye diseases

CR Harrell, V Djonov, A Antonijevic, V Volarevic - Cells, 2023 - mdpi.com
Due to their potent immunoregulatory and angio-modulatory properties, mesenchymal stem
cells (MSCs) and their exosomes (MSC-Exos) have emerged as potential game-changers in …

[HTML][HTML] Indoleamine 2, 3-dioxygenase mediates the therapeutic effects of adipose-derived stromal/stem cells in experimental periodontitis by modulating …

H Li, Y Yuan, H Chen, H Dai, J Li - Molecular Metabolism, 2022 - Elsevier
Objectives Mesenchymal stromal/stem cell (MSC)-based therapy has become a promising
approach to periodontal tissue repair. Adipose-derived stromal/stem cells (ASCs), compared …

The therapeutic potential of dietary intervention: based on the mechanism of a tryptophan derivative-indole propionic acid on metabolic disorders

B Niu, T Pan, Y Xiao, H Wang, J Zhu… - Critical Reviews in …, 2023 - Taylor & Francis
Tryptophan (TRP) contributes to individual immune homeostasis and good condition via
three complex metabolism pathways (5-hydroxytryptamine (5-HT), kynurenine (KP), and gut …

Recent Advancements in Bone Tissue Engineering: Integrating Smart Scaffold Technologies and Bio-Responsive Systems for Enhanced Regeneration

KM Percival, V Paul, GA Husseini - International Journal of Molecular …, 2024 - mdpi.com
In exploring the challenges of bone repair and regeneration, this review evaluates the
potential of bone tissue engineering (BTE) as a viable alternative to traditional methods …

METTL3 potentiates osteogenic differentiation of bone marrow mesenchymal stem cells via IGF2BP1/m6A/RUNX2

S Zhou, G Zhang, K Wang, Z Yang, Y Tan - Oral Diseases, 2024 - Wiley Online Library
Objective Maxillofacial bone defect is a critical obstacle for maxillofacial tumors and
periodontal diseases. The osteogenic differentiation of bone marrow mesenchymal stem …

Structural characterization and immunomodulatory activity of an exopolysaccharide from marine-derived Aspergillus versicolor SCAU141

K Wu, Y Li, Y Lin, B Xu, J Yang, L Mo, R Huang… - International Journal of …, 2023 - Elsevier
Until now, relatively little is known about marine-derived fungal polysaccharides and their
activities. Exopolysaccharide AVP141-A was isolated from the broth of marine-derived …

[HTML][HTML] Cell primitive-based biomimetic nanomaterials for Alzheimer's disease targeting and therapy

T Yin, Y Liu, B He, B Gong, J Chu, C Gao, W Liang… - Materials Today Bio, 2023 - Elsevier
Alzheimer's disease (AD) is a progressive neurodegenerative disorder, which is not just
confined to the older population. Although developments have been made in AD treatment …

LC–MS/MS-based quantification of tryptophan, kynurenine, and kynurenic acid in human placental, fetal membranes, and umbilical cord samples

B Pedraz-Petrozzi, M Marszalek-Grabska, A Kozub… - Scientific Reports, 2023 - nature.com
Tryptophan breakdown metabolites formed along the kynurenine pathway play a significant
role in pregnancy and fetal development. To understand their involvement, it is crucial to …

Mitochondria in Mesenchymal Stem Cells: Key to Fate Determination and Therapeutic Potential

Y Liu, L Wang, J Ai, K Li - Stem Cell Reviews and Reports, 2024 - Springer
Mesenchymal stem cells (MSCs) have become popular tool cells in the field of
transformation and regenerative medicine due to their function of cell rescue and cell …