Genital tract carriage of group B streptococcus (GBS) is prevalent among adult women;
however, the dynamics of chronic GBS genital tract carriage, including how GBS persists in …

Granulocyte-macrophage colony-stimulating factor (GM-CSF) has been known as a
hematopoietic growth factor and immune modulator. Recent studies revealed that GM-CSF …

Immunity to fungal infections is mediated by cells of the innate and adaptive immune system
including Th17 cells. Ca2+ influx in immune cells is regulated by stromal interaction …

In multiple sclerosis (MS), there is a growing interest in inhibiting the pro-inflammatory
effects of granulocyte-macrophage colony-stimulating factor (GM-CSF). We sought to …

Experimental autoimmune encephalomyelitis (EAE) has been used as an animal model of
multiple sclerosis to identify pathogenic cytokines that could be therapeutic targets …

Current literature consolidates the view of Crohn's disease (CD) as a form of
immunodeficiency highlighting dysregulation of intestinal innate immunity in the …

Cytokines made by macrophages play a critical role in determining the course of Legionella
pneumophila infection. Prior murine-based modeling indicated that this cytokine response is …

Sarcomas are a relatively rare cancer, but often incurable at the late metastatic stage.
Oncolytic immunotherapy has gained attention over the past years, and a wide range of …

Inflammatory bowel disease (IBD), consisting of ulcerative colitis and Crohn's disease,
mainly affects the gastrointestinal tract but is also known to have extraintestinal …

We recently demonstrated Ang 1–7 reduced inflammation in the dextran sulfate sodium
(DSS) colitis model. In this study we examined the effect of Ang 1–7 on modulation of …