Measured Steps: Navigating the Path of Oligoprogressive Lung Cancer with Targeted and Immunotherapies

M Jongbloed, AA Khosla, V Bartolomeo… - Current oncology …, 2024 - Springer
Abstract Purpose of Review This review discusses the definitions, treatment modalities,
management, future directions, and ongoing clinical trials of oligoprogressive disease in …

[HTML][HTML] First-versus third-generation EGFR tyrosine kinase inhibitors in EGFR-mutated non-small cell lung cancer patients with brain metastases

V Tatineni, PJ O'Shea, A Ozair, AA Khosla, S Saxena… - Cancers, 2023 - mdpi.com
Simple Summary Targeted therapies have emerged as newer systemic options for certain
cancers. EGFR-directed Tyrosine Kinase Inhibitors (EGFR-TKIs), which have several …

Epidermal Growth Factor Receptor Inhibitors for Lung Cancer and the Risk of Keratitis

PC Huang, CC Lin, R Dana, KSK Ma - JAMA ophthalmology, 2024 - jamanetwork.com
Importance Epidermal growth factor receptor inhibitors (EGFRis) have been reported to be
associated with cutaneous and ocular side effects; however, there is limited evidence of an …

[HTML][HTML] The difference between dacomitinib and afatinib in effectiveness and safety in first-line treatment of patients with advanced EGFR-mutant non-small cell lung …

WC Cheng, CC Lin, WC Liao, YC Lin, CH Chen… - BMC cancer, 2024 - Springer
Objectives The irreversible epidermal growth factor receptor tyrosine kinase inhibitors
(EGFR TKIs) afatinib and dacomitinib are approved for first-line treatment of EGFR mutation …

[HTML][HTML] Osimertinib versus comparator first-generation epidermal growth factor receptor tyrosine kinase inhibitors as first-line treatment in patients with advanced …

D Zhang, X Liu, F Shen, D Zhao, Y Shi… - Translational Lung …, 2023 - ncbi.nlm.nih.gov
Background In the phase 3 FLAURA trial, osimertinib was compared with first-generation
epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) as a first-line …

Treatment outcomes of non-small cell lung cancers treated with EGFR tyrosine kinase inhibitors: a real-world cohort study

O Manninen, L Puuniemi, S Iivanainen, M Arffman… - Acta …, 2023 - Taylor & Francis
Background Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKI) are a
standard of care treatment options in non-small cell lung cancer (NSCLC). The present study …

[HTML][HTML] Improvement in survival for patients with lung cancer in Taiwan: implications and call to action

F Oezkan, M Seweryn, T Shukuya, DH Owen - Journal of Thoracic …, 2023 - Elsevier
Lung cancer screening by low-dose computed tomography (LDCT) scan has been initiated
in several countries around the globe after large-scale studies revealed a significant …

Optimal First-Line Treatment for EGFR-Mutated NSCLC: A Comparative Analysis of Osimertinib and Second-Generation EGFR-TKIs

HY Chen, CH Chen, WC Liao, YC Lin, HJ Chen… - 2024 - researchsquare.com
Background Osimertinib is an irreversible third-generation epidermal growth factor receptor
(EGFR) tyrosine kinase inhibitor (TKI). It is the preferred first-line treatment for EGFR-mutated …