Contemporary challenges in the design of topoisomerase II inhibitors for cancer chemotherapy
C Bailly - Chemical reviews, 2012 - ACS Publications
1. INTRODUCTION The length of straightened-out DNA in a single cell is nearly 2 m. In
mammalian cells, the nucleus has a diameter of approximately 6 μm and occupies about …
mammalian cells, the nucleus has a diameter of approximately 6 μm and occupies about …
[HTML][HTML] Natural Products–Pyrazine Hybrids: A Review of Developments in Medicinal Chemistry
GQ Chen, HY Guo, ZS Quan, QK Shen, X Li, T Luan - Molecules, 2023 - mdpi.com
Pyrazine is a six-membered heterocyclic ring containing nitrogen, and many of its
derivatives are biologically active compounds. References have been downloaded through …
derivatives are biologically active compounds. References have been downloaded through …
Synthesis of novel fluorescent benzo [a] pyrano [2, 3-c] phenazine and benzo [a] chromeno [2, 3-c] phenazine derivatives via facile four-component domino protocol
P Saluja, A Chaudhary, JM Khurana - Tetrahedron letters, 2014 - Elsevier
An efficient and practical route to novel fluorescent benzo [a] pyrano [2, 3-c] phenazine
framework has been developed by one-pot, four-component reaction of 2 …
framework has been developed by one-pot, four-component reaction of 2 …
Discovery and structure–activity relationship of plastoquinone analogs as anticancer agents against chronic myelogenous leukemia cells
Abstract Two series of amino‐1, 4‐benzoquinones (AQ1–18) based on the structural
analogs of plastoquinones were synthesized and the structure–activity relationship against …
analogs of plastoquinones were synthesized and the structure–activity relationship against …
One-Pot Synthesis of Spiro-isobenzofuran Compounds via the Sequential Condensation/Oxidation Reaction of Ninhydrin with 4-Amino-1,2-naphthoquinones/2 …
SH Mousavi, MR Mohammadizadeh, Z Roshan… - ACS …, 2020 - ACS Publications
A one-pot route for the synthesis of spiro-isobenzofuran compounds was developed via the
condensation reaction of ninhydrin with 4-amino-1, 2-naphthoquinones or 2-amino-1, 4 …
condensation reaction of ninhydrin with 4-amino-1, 2-naphthoquinones or 2-amino-1, 4 …
Synthesis and cytotoxicity of 2-phenylquinazolin-4 (3H)-one derivatives
Thirty 2-phenylquinazolin-4 (3H)-one derivatives were prepared and their cytotoxic activities
were tested in five human tumor cell lines. Some compounds (5e, 5k, 5t, 6c and 6f) showed …
were tested in five human tumor cell lines. Some compounds (5e, 5k, 5t, 6c and 6f) showed …
Caffeine catalyzed green synthesis of novel benzo [a][1, 3] oxazino [6, 5-c] phenazines via a one-pot multi-component sequential protocol in a basic ionic liquid
R Mohebat, A Yazdani-Elah-Abadi - Chinese Chemical Letters, 2017 - Elsevier
Caffeine was applied as a green and natural catalyst for the one-pot, four-component
sequential condensation between 2-hydroxy-1, 4-naphthoquinone, aromatic 1, 2-diamines …
sequential condensation between 2-hydroxy-1, 4-naphthoquinone, aromatic 1, 2-diamines …
DABCO-catalyzed multi-component domino reactions for green and efficient synthesis of novel 3-oxo-3H-benzo [a] pyrano [2, 3-c] phenazine-1-carboxylate and 3-(5 …
R Mohebat, A Yazdani-Elah-Abadi… - Chinese Chemical …, 2017 - Elsevier
An efficient, convenient and environmentally benign procedure for the synthesis of novel 3-
oxo-3H-benzo [a] pyrano [2, 3-c] phenazine-1-carboxylate and 3-(5-hydroxybenzo [a] …
oxo-3H-benzo [a] pyrano [2, 3-c] phenazine-1-carboxylate and 3-(5-hydroxybenzo [a] …
Synthesis, antiproliferative activity and molecular docking studies of novel benzo [a] pyrano-[2, 3-c] phenazine derivatives
P Nagaraju, PN Reddy, P Padmaja, VG Ugale - Chemical Data Collections, 2020 - Elsevier
A new one pot three-component reaction for the synthesis of benzo [a] pyrano-[2, 3-c]
phenazine derivatives has been developed. The synthesis was achieved by reacting benzo …
phenazine derivatives has been developed. The synthesis was achieved by reacting benzo …
Microwave-assisted and L-proline catalysed domino cyclisation in an aqueous medium: a rapid, highly efficient and green synthesis of benzo [a] phenazine annulated …
A Yazdani-Elah-Abadi, R Mohebat… - Journal of Chemical …, 2016 - journals.sagepub.com
A highly efficient one-pot, two-step microwave-assisted procedure was applied for the rapid
and green synthesis of benzo [a] phenazine annulated heterocyclic ring systems from the …
and green synthesis of benzo [a] phenazine annulated heterocyclic ring systems from the …