Mind the gaps: what we don't know about cognitive impairment in essential tremor

ED Louis, JL Joyce, S Cosentino - Parkinsonism & Related Disorders, 2019 - Elsevier
Introduction Although the hallmark feature of essential tremor (ET) is tremor, there is growing
appreciation that cognitive impairment also occurs, including increased prevalence of mild …

[HTML][HTML] Cyclic glycine-proline (cGP) normalises insulin-like growth factor-1 (IGF-1) function: Clinical significance in the ageing brain and in age-related neurological …

J Guan, F Li, D Kang, T Anderson, T Pitcher… - Molecules, 2023 - mdpi.com
Insulin-like growth factor-1 (IGF-1) function declines with age and is associated with brain
ageing and the progression of age-related neurological conditions. The reversible binding of …

Sex differences in progression to mild cognitive impairment and dementia in Parkinson's disease

B Cholerton, CO Johnson, B Fish, JF Quinn… - Parkinsonism & related …, 2018 - Elsevier
Introduction Identification of factors associated with progression of cognitive symptoms in
Parkinson's disease (PD) is important for treatment planning, clinical care, and design of …

[PDF][PDF] The effects of probiotic supplementation on gene expression related to inflammation, insulin and lipid in patients with Parkinson's disease: a randomized …

S Borzabadi, S Oryan, A Eidi, Z Asemi - Archives of Iranian medicine, 2018 - journalaim.com
Background: This study was conducted to evaluate the effects of probiotic supplementation
on gene expression related to inflammation, insulin and lipid in patients with Parkinson's …

Magnetic resonance imaging–visible perivascular spaces in basal ganglia predict cognitive decline in Parkinson's disease

YW Park, NY Shin, SJ Chung, J Kim, SM Lim… - Movement …, 2019 - Wiley Online Library
Background Growing evidence suggests an association between imaging biomarkers of
small vessel disease and future cognitive decline in Parkinson's disease (PD). Recently …

[HTML][HTML] The Quebec Parkinson network: a researcher-patient matching platform and multimodal biorepository

Z Gan-Or, T Rao, E Leveille, C Degroot… - Journal of …, 2020 - content.iospress.com
Background: Genetic, biologic and clinical data suggest that Parkinson's disease (PD) is an
umbrella for multiple disorders with clinical and pathological overlap, yet with different …

Modifiable vascular risk factors, white matter disease and cognition in early Parkinson's disease

LM Chahine, C Dos Santos, M Fullard… - European journal of …, 2019 - Wiley Online Library
Background and purpose Dementia in Parkinson's disease (PD) is common and disabling.
Identification of modifiable risk factors for it is essential. Vascular risk factors (VRFs) may be …

[HTML][HTML] A Possible Role for HMG-CoA Reductase Inhibitors and Its Association with HMGCR Genetic Variation in Parkinson's Disease

A Pierzchlińska, M Droździk, M Białecka - International Journal of …, 2021 - mdpi.com
Parkinson's disease (PD) is the second most common neurodegenerative disease
characterised by both motor-and non-motor symptoms, including cognitive impairment. The …

[HTML][HTML] Effect of Metabolic Syndrome on Parkinson's Disease: A Systematic Review

APS Souza, WMA Barros, JML Silva, MRM Silva… - Clinics, 2021 - SciELO Brasil
Evidence shows that metabolic syndrome (MS) is associated with a greater risk of
developing Parkinson's disease (PD) because of the increase in oxidative stress levels …

Cardiovascular dysautonomia and cognition in Parkinson's disease—a possible relationship

M Kwaśniak-Butowska, J Dulski… - Neurologia i …, 2021 - journals.viamedica.pl
Dementia in advanced Parkinson's Disease (PD) is a fatal milestone resulting in reduced life
expectancy and nursing home placement. Cognitive impairment and cardiovascular …