Platelets are involved in the pathogenesis of vascular damage in both atherosclerosis and
arterial hypertension. Their reactivity in vivo is influenced by different factors, including …

A series of 8-substituted quinolines were synthesized and tested against seizures induced
by maximal electro shock (MES), pentylenetetrazole (scMet) and antihypertensive activities …

The past decade has shown an obvious rediscovery of the interest in a-adrenoceptorsl. This
renaissance of interest is explained by the discovery of pre-and postsynaptic(postjunctional) …

The receptor mediating the long‐lasting hypotensive effect of intravenous (iv) 5‐
hydroxytryptamine (5‐HT) in the rat was originally classified as 5‐HT1‐like. Since some …

The ability of the putative serotonin 2 (5-HT 2) antagonist ketanserin, to alter serotonin (5-
HT)-induced responses in cell firing was examined in the prefrontal cortex, the lateral …

Abstract The pharmacological activity of 3−((4−(2− methoxyphenyl) piperazin− 1− yl)
methyl)− 2, 3− dihydroimidazo (1, 2− c) quinazolin− 5 (6H)-one (DC− 015), a newly …

A series of 1-substituted pyrrolidin-2-one and pyrrolidine derivatives were synthesised and
tested for electrocardiographic, antiarrhythmic, and antihypertensive activity as well as for α1 …

Extract from seeds and bark of horse chestnut (Aesculus hippocastanum L) is used as an
herbal medicine against chronic venous insufficiency. The effect and mechanism of action …

In vitro affinity for vascular 5HT2 and alpha receptors was determined for several
compounds (spiperone, ketanserin, mianserin, trazodone, mepiprazole, benzoctamine, m …

Behavioural and neurochemical effects of acute 1-methyl-4-phenyl-1, 2, 3, 6-
tetrahydropyridine (MPTP) treatment in mice have been studied in order to determine the …