Slc6a14 and Slc38a5 drive the glutaminolysis and serine–Glycine–One-Carbon pathways in cancer
T Sniegowski, K Korac, YD Bhutia, V Ganapathy - Pharmaceuticals, 2021 - mdpi.com
The glutaminolysis and serine–glycine–one-carbon pathways represent metabolic reactions
that are reprogramed and upregulated in cancer; these pathways are involved in supporting …
that are reprogramed and upregulated in cancer; these pathways are involved in supporting …
[HTML][HTML] Amino Acid Transporter SLC6A14 (ATB0,+) – A Target in Combined Anti-cancer Therapy
KA Nałęcz - Frontiers in cell and developmental biology, 2020 - frontiersin.org
Cancer cells are characterized by quick growth and proliferation, demanding constant
supply of various nutrients. Several plasma membrane transporters delivering such …
supply of various nutrients. Several plasma membrane transporters delivering such …
[HTML][HTML] HnRNPR-CCNB1/CENPF axis contributes to gastric cancer proliferation and metastasis
EB Chen, X Qin, K Peng, Q Li, C Tang, YC Wei… - Aging (Albany …, 2019 - ncbi.nlm.nih.gov
Gastric cancer (GC) is a common disease globally with high mortality rate. It is therefore
necessary to develop novel therapies targeting specific events in the pathogenesis of GC …
necessary to develop novel therapies targeting specific events in the pathogenesis of GC …
TMC4 is a novel chloride channel involved in high-concentration salt taste sensation
Y Kasahara, M Narukawa, Y Ishimaru, S Kanda… - The Journal of …, 2021 - Springer
Abstract “Salty taste” sensation is evoked when sodium and chloride ions are present
together in the oral cavity. The presence of an epithelial cation channel that receives Na+ …
together in the oral cavity. The presence of an epithelial cation channel that receives Na+ …
[HTML][HTML] Early diagnosis of pancreatic ductal adenocarcinoma by combining relative expression orderings with machine-learning method
ZM Zhang, JS Wang, H Zulfiqar, H Lv… - Frontiers in Cell and …, 2020 - frontiersin.org
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive and lethal cancer deeply
affecting human health. Diagnosing early-stage PDAC is the key point to PDAC patients' …
affecting human health. Diagnosing early-stage PDAC is the key point to PDAC patients' …
Development and clinical validation of a novel 9-gene prognostic model based on multi-omics in pancreatic adenocarcinoma
D Xu, Y Wang, X Liu, K Zhou, J Wu, J Chen… - Pharmacological …, 2021 - Elsevier
The prognoses of patients with pancreatic adenocarcinoma (PAAD) remain poor due to the
lack of biomarkers for early diagnosis and effective prognosis prediction. RNA sequencing …
lack of biomarkers for early diagnosis and effective prognosis prediction. RNA sequencing …
Robust identification of common genomic biomarkers from multiple gene expression profiles for the prognosis, diagnosis, and therapies of pancreatic cancer
Pancreatic cancer (PC) is one of the leading causes of cancer-related death globally. So,
identification of potential molecular signatures is required for diagnosis, prognosis, and …
identification of potential molecular signatures is required for diagnosis, prognosis, and …
Clinical significance and diagnostic value of QPCT, SCEL and TNFRSF12A in papillary thyroid cancer
T Liang, X Wu, L Wang, Z Ni, Y Fan, P Wu… - … -Research and Practice, 2023 - Elsevier
Purpose To identify specific novel genes that could be used as diagnostic and prognostic
factors in papillary thyroid carcinoma (PTC). Methods Screening of differential genes by …
factors in papillary thyroid carcinoma (PTC). Methods Screening of differential genes by …
Exosome‐mediated lncRNA SNHG11 regulates angiogenesis in pancreatic carcinoma through miR‐324‐3p/VEGFA axis
X Fang, Y Cai, Y Xu, H Zhang - Cell Biology International, 2022 - Wiley Online Library
Pancreatic carcinoma (PC) is one of the most common and deadly human malignancies
worldwide. LncRNAs play significant roles in the occurrence and development of various …
worldwide. LncRNAs play significant roles in the occurrence and development of various …
Immune cell modulation of the extracellular matrix contributes to the pathogenesis of pancreatic cancer
RS Ahmad, TD Eubank, S Lukomski, BA Boone - Biomolecules, 2021 - mdpi.com
Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal malignancy with a five-year
survival rate of only 9%. PDAC is characterized by a dense, fibrotic stroma composed of …
survival rate of only 9%. PDAC is characterized by a dense, fibrotic stroma composed of …