EPYC functions as a novel prognostic biomarker for pancreatic cancer

Z Yang, H Li, J Hao, H Mei, M Qiu, H Wang, M Gao - Scientific Reports, 2024 - nature.com
Pancreatic cancer (PC) has become a worldwide challenge attributed to its difficult early
diagnosis and rapid progression. Treatments continue to be limited besides surgical …

Molecular logic of salt taste reception in special reference to transmembrane channel-like 4 (TMC4)

Y Kasahara, M Narukawa, A Takeuchi… - The Journal of …, 2022 - Springer
The taste is biologically of intrinsic importance. It almost momentarily perceives
environmental stimuli for better survival. In the early 2000s, research into taste reception was …

Immune cell modulation of the extracellular matrix contributes to the pathogenesis of pancreatic cancer

RS Ahmad, TD Eubank, S Lukomski, BA Boone - Biomolecules, 2021 - mdpi.com
Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal malignancy with a five-year
survival rate of only 9%. PDAC is characterized by a dense, fibrotic stroma composed of …

Role of Sciellin in gallbladder cancer proliferation and formation of neutrophil extracellular traps

Y Li, R Yuan, T Ren, B Yang, H Miao, L Liu, Y Li… - Cell Death & …, 2021 - nature.com
Apart from primary tumor development and metastasis, cancer-associated thrombosis is the
second cause of cancer death in solid tumor malignancy. However, the mechanistic insight …

TSPAN1, TMPRSS4, SDR16C5, and CTSE as Novel Panel for Pancreatic Cancer: A Bioinformatics Analysis and Experiments Validation

H Ye, T Li, H Wang, J Wu, C Yi, J Shi, P Wang… - Frontiers in …, 2021 - frontiersin.org
Pancreatic cancer is a lethal malignancy with a poor prognosis. This study aims to identify
pancreatic cancer-related genes and develop a robust diagnostic model to detect this …

Clinical significance and diagnostic value of QPCT, SCEL and TNFRSF12A in papillary thyroid cancer

T Liang, X Wu, L Wang, Z Ni, Y Fan, P Wu… - … -Research and Practice, 2023 - Elsevier
Purpose To identify specific novel genes that could be used as diagnostic and prognostic
factors in papillary thyroid carcinoma (PTC). Methods Screening of differential genes by …

Integrated bioinformatic analysis identifies networks and promising biomarkers for hepatitis B virus‐related hepatocellular carcinoma

Y Ji, Y Yin, W Zhang - International Journal of Genomics, 2020 - Wiley Online Library
Chronic infection with hepatitis B virus (HBV) has long been recognized as a dominant
hazard factor for hepatocellular carcinoma (HCC) and accounts for at least half of HCC …

CBX8 promotes lung adenocarcinoma growth and metastasis through transcriptional repression of CDKN2C and SCEL

H Chen, Y Su, L Yang, L Xi, X Li, B Lan… - Journal of Cellular …, 2023 - Wiley Online Library
Dysregulation of polycomb group (PcG) proteins that mediate epigenetic gene silencing
contributes to tumorigenesis. As core components of the polycomb repressive complex 1 …

Role of tumor mutation burden-related signatures in the prognosis and immune microenvironment of pancreatic ductal adenocarcinoma

R Tang, X Liu, W Wang, J Hua, J Xu, C Liang… - Cancer cell …, 2021 - Springer
Background High tumor mutation burden (TMB) has gradually become a sensitive biomarker
for predicting the response to immunotherapy in many cancers, including lung, bladder and …

Identification of candidate diagnostic and prognostic biomarkers for human prostate cancer: RPL22L1 and RPS21

Z Liang, Q Mou, Z Pan, Q Zhang, G Gao, Y Cao, Z Gao… - Medical Oncology, 2019 - Springer
Prostate cancer (PCa) is one of the most common malignancies in men worldwide. This
study was designed to investigate the potential of Ribosomal Protein L22-like1 (RPL22L1) …