[HTML][HTML] Identification of novel prognostic biomarkers in renal cell carcinoma

Y Zou, Q Lu, Q Yao, D Dong, B Chen - Aging (Albany NY), 2020 - ncbi.nlm.nih.gov
Results: 12 coding genes and one miRNA were finally identified as prognostic biomarkers.
All of them were related to a poor prognosis. Lower expression levels of the coding genes …

[HTML][HTML] A prognostic model of pancreatic cancer based on ferroptosis-related genes to determine its immune landscape and underlying mechanisms

X Yu, Q Zheng, M Zhang, Q Zhang, S Zhang… - Frontiers in cell and …, 2021 - frontiersin.org
Pancreatic cancer is one of the malignant tumors with the worst prognosis in the world. As a
new way of programmed cell death, ferroptosis has been proven to have potential in tumor …

Development and validation of a ferroptosis-related prognostic model in pancreatic cancer

C Qiu, X Wang, Z Zheng, C Yang, K Lin, K Zhang… - Investigational New …, 2021 - Springer
Background: The purpose of this study was to identify ferroptosis-related genes (FRGs)
associated with the prognosis of pancreatic cancer and to construct a prognostic model …

[HTML][HTML] TMPRSS4 promotes cell proliferation and inhibits apoptosis in pancreatic ductal adenocarcinoma by activating ERK1/2 signaling pathway

J Gu, W Huang, J Zhang, X Wang, T Tao, L Yang… - Frontiers in …, 2021 - frontiersin.org
Transmembrane protease serine 4 (TMPRSS4) is upregulated in various kinds of human
cancers, including pancreatic cancer. However, its biological function in pancreatic ductal …

[HTML][HTML] TMPRSS4: a novel tumor prognostic indicator for the stratification of stage IA tumors and a liquid biopsy biomarker for NSCLC patients

M Villalba, F Exposito, MJ Pajares, C Sainz… - Journal of Clinical …, 2019 - mdpi.com
Relapse rates in surgically resected non-small-cell lung cancer (NSCLC) patients are
between 30% and 45% within five years of diagnosis, which shows the clinical need to …

[HTML][HTML] Systematic analysis of an invasion-related 3-gene signature and its validation as a prognostic model for pancreatic cancer

D Xu, Y Wang, Y Zhang, Z Liu, Y Chen… - Frontiers in …, 2021 - frontiersin.org
Background Pancreatic adenocarcinoma (PAAD) is a malignant tumor of the digestive
system that is associated with a poor prognosis in patients owing to its rapid progression …

[HTML][HTML] Interferon regulatory factor 5‑induced upregulation of zinc‑finger protein 217 promotes pancreatic carcinoma progression

X Qiao, S Lv, Y Qiao, F Wang… - Molecular Medicine …, 2022 - spandidos-publications.com
The aim of the present study was to investigate the molecular mechanisms of zinc‑finger
protein 217 (ZNF217) in pancreatic carcinoma (PC) progression. ZNF217‑associated …

Metabolism‐Related Bioinformatics Analysis Reveals That HPRT1 Facilitates the Progression of Oral Squamous Cell Carcinoma In Vitro

H Ye, Z Zheng, Y Song, G Huang, Q Wu… - Journal of …, 2022 - Wiley Online Library
Objectives. Many studies have shown that dysregulation of metabolism contributes to
oncogenesis. However, the exact roles of metabolism‐related genes (MRGs) in oral …

Type II transmembrane serine proteases 4 (TMPRSS4) promotes proliferation, invasion and epithelial–mesenchymal transition in endometrial carcinoma cells …

H Xiao, Z Zhang, D Peng, C Wei, B Ma - Animal Cells and Systems, 2021 - Taylor & Francis
Endometrial cancer is the most common gynecological cancer in the developed countries.
Type II transmembrane serine proteases 4 (TMPRSS4) is a newly discovered …

Development and validation of a four‐lipid metabolism gene signature for diagnosis of pancreatic cancer

Y Ye, Z Chen, Y Shen, Y Qin, H Wang - FEBS Open Bio, 2021 - Wiley Online Library
Abnormal lipid metabolism is closely related to the malignant biological behavior of tumor
cells. Such abnormal lipid metabolism provides energy for rapid proliferation, and certain …