Association of the TGFβ gene family with microenvironmental features of gastric cancer and prediction of response to immunotherapy
B Han, T Fang, Y Zhang, Y Zhang, J Gao… - Frontiers in …, 2022 - frontiersin.org
In the complex tumor microenvironment, TGFβ is a pleiotropic cytokine involved in regulating
cellular processes such as cancer cell proliferation, apoptosis and metastasis. TGFβ defines …
cellular processes such as cancer cell proliferation, apoptosis and metastasis. TGFβ defines …
Effects of transmembrane serine protease 4 on the survival in patients with pancreatic ductal adenocarcinoma undergoing surgery followed by adjuvant chemotherapy
S Tazuma, T Sudo, A Ishikawa, A Yamaguchi… - Surgery Today, 2024 - Springer
Purpose The transmembrane serine protease 4 (TMPRSS4) gene is upregulated in various
human cancers. However, its biological functions in pancreatic ductal adenocarcinoma …
human cancers. However, its biological functions in pancreatic ductal adenocarcinoma …
Molecular signatures of tumor progression in pancreatic adenocarcinoma identified by energy metabolism characteristics
C Tan, X Wang, X Wang, W Weng, S Ni, M Zhang… - BMC cancer, 2022 - Springer
Background In this study, we performed a molecular evaluation of primary pancreatic
adenocarcinoma (PAAD) based on the comprehensive analysis of energy metabolism …
adenocarcinoma (PAAD) based on the comprehensive analysis of energy metabolism …
Multiomics data analysis and identification of immune-related prognostic signatures with potential implications in prognosis and immune checkpoint blockade therapy …
S Ma, F Wang, N Wang, J Jin, Y Ba, H Ji, J Du… - Frontiers in …, 2022 - frontiersin.org
Background In recent years, glioblastoma multiforme (GBM) has been a concern of many
researchers, as it is one of the main drivers of cancer-related deaths worldwide. GBM in …
researchers, as it is one of the main drivers of cancer-related deaths worldwide. GBM in …
A Risk‐Assessing Signature Based on Hypoxia‐and Immune‐Related Genes for Prognosis of Lung Adenocarcinoma Patients
Y Wang, J Feng, Y Liu, T Han - … and Mathematical Methods in …, 2022 - Wiley Online Library
Lung Adenocarcinoma (LUAD) drastically influences human health. Tumor hypoxia and
immunity impact hugely on the immunotherapeutic effect of LUAD patients. This study is …
immunity impact hugely on the immunotherapeutic effect of LUAD patients. This study is …
Exploration of the cancer genome atlas database reveals genes of interest related with cancer cell stemness indices in clear cell renal cell carcinoma
S Xing, X Ruan, C Zhang, D Xu, L Chen - Heliyon, 2022 - cell.com
Heterogeneity of kidney cancer poses great challenges in clinical management. Practicians
are still in need of an effective way to identify high-risk patients. Here we browsed big data …
are still in need of an effective way to identify high-risk patients. Here we browsed big data …
Identification by genetic algorithm optimized back propagation artificial neural network and validation of a four-gene signature for diagnosis and prognosis of …
Background Although some improvements in the management of pancreatic cancer (PC)
have been made, no major breakthroughs in terms of biomarker discovery or effective …
have been made, no major breakthroughs in terms of biomarker discovery or effective …
Integrated Analysis of Multi-Omics Data to Identify Prognostic Genes for Pancreatic Cancer
F Jiang, X Huang, F Zhang, J Pan, J Wang… - DNA and Cell …, 2022 - liebertpub.com
Pancreatic cancer (PC) is a common cause of cancer-related deaths. Current research
shows that prognostic biomarkers play a key role in the treatment of PC. This study aimed to …
shows that prognostic biomarkers play a key role in the treatment of PC. This study aimed to …
Improper Proteostasis: Can It Serve as Biomarkers for Neurodegenerative Diseases?
AR Dubey, SM Patwa, S Kinger, YA Jagtap… - Molecular …, 2022 - Springer
Cells synthesize new proteins after multiple molecular decisions. Damage of existing
proteins, accumulation of abnormal proteins, and basic requirement of new proteins trigger …
proteins, accumulation of abnormal proteins, and basic requirement of new proteins trigger …
[PDF][PDF] 溶质转运体在消化系统肿瘤中的研究进展
林佳莉， 李洁， 袁继行 - 生命科学, 2022 - lifescience.sinh.ac.cn
溶质转运体(solute carriers, SLCs) 超家族是生物丰度位列第二的人体膜转运蛋白, 仅次于G
蛋白偶联受体. 它不仅在生理条件下介导分子或离子转运进而调节细胞功能, 在病理条件下 …
蛋白偶联受体. 它不仅在生理条件下介导分子或离子转运进而调节细胞功能, 在病理条件下 …