[HTML][HTML] Inhibition of glutamine metabolism as a therapeutic approach against pancreatic ductal adenocarcinoma

XF Miguel, MP José - Journal of Molecular and Clinical Medicine, 2019 - imrpress.com
Pancreatic ductal adenocarcinoma (PDAC) is a relatively rare tumor, however it is the
seventh cancer related leading cause of death worldwide. Mean survival time after PDAC …

Integrative Analysis Developing and Validating Potential Candidate Biomarkers for Cancer Stemness Features of Pan-Renal Cell Carcinoma

F Lin, ZB Ke, H Chen, WC Zheng, RN Dong… - Cancer …, 2023 - Taylor & Francis
In our study, 49 key genes significantly associated with renal cell carcinoma (RCC)
stemness were obtained. Next, we developed a molecular prognostic signature associated …

System Analysis Based on Pancreatic Cancer Progression Identifies BRINP2 as a Novel Prognostic Biomarker

Y Kang, X Xu, J Liu - Critical Reviews™ in Eukaryotic Gene …, 2023 - dl.begellhouse.com
Pancreatic adenocarcinoma (PAAD) is a malignant tumor of the digestive system, which
develops rapidly and has no obvious early symptoms. This study aims to discover the …

CENPF Upregulation is Associated with Immunosuppressive Status and Poor Clinical Outcomes in Lung Adenocarcinoma Validated by qRT-PCR

Z Xu, D Xu, Z You, W Tian - Combinatorial Chemistry & High …, 2024 - ingentaconnect.com
Objective: CENPF-differentially expressed in various types of cancers128;” is a marker of
poor prognosis. However, studies on the impact of CENPF on patient prognosis in lung …

Comprehensive Bioinformatic Analysis for Identification of Crucial Genes and Signaling Transduction Pathways in Head and Neck Squamous Cell Carcinoma

J Cheon, B Kim, J Byun, S Jung, J Kim, S Kwak, J Shin… - 2024 - researchsquare.com
Head and neck squamous cell carcinoma (HNSCC) is a prevalent global cancer, ranking
sixth in incidence. Investigating the molecular basis of tumorigenesis and metastasis is …

[HTML][HTML] A Rare Case of Metastasis to the Pancreas From a Primary Transitional-Cell Urinary Bladder Carcinoma

LH Rathod, S Ferdous, MB Wanjari - Cureus, 2022 - ncbi.nlm.nih.gov
Pancreatic cancer (PC) occurs when changes (mutations) in the pancreas cells lead them to
multiply out of control. A mass of tissue can result. Sometimes, this mass is benign (not …

[HTML][HTML] Identification and validation of a ten-gene set variation score as a diagnostic and prognostic stratification tool in hepatocellular carcinoma

C Zou, C Yuan, J Ye, Z Liu, X Gao, X Piao… - American Journal of …, 2020 - ncbi.nlm.nih.gov
We aimed to identify a hepatocellular carcinoma (HCC)-specific gene set during
progression. Using the HCC data set from The Cancer Genome Atlas, we found that 10 …

The interleukin expression pattern relates to cancer associated fibroblasts infiltration and immunotherapy response in pancreatic carcinoma

Y Cheng, S Xiao, Y Lei, L Ma, X Li, B Wang, P Sun… - 2024 - researchsquare.com
Background: Cancer associated fibroblasts (CAFs) and the interleukin (IL) family have been
reported to play crucial roles in immune response in pancreatic carcinoma (PC). However …

Integrative analyses of bulk, single-cell and spatial transcriptomics identified diabetes mellitus-related signature as a prognostic factor in pancreatic adenocarcinoma

L Tang, T Xie, G Fan, H Zhu, J Yao, Y Shi - 2023 - researchsquare.com
Purpose Pancreatic adenocarcinoma (PAAD) is a deadly disease, particularly for those with
diabetes mellitus (DM). While there have been various studies on prognostic factors in …

Ribosomal Biogenesis and Endomembrane Expansion Precede Cell Invasion

DS Costa - 2023 - search.proquest.com
Cell invasion through basement membrane (BM) barriers is necessary for development, and
homeostasis, and is misappropriated in diseases like cancer. Many regulators of this …