Curcumin: an inflammasome silencer

S Hasanzadeh, MI Read, AR Bland, M Majeed… - Pharmacological …, 2020 - Elsevier
Curcumin is the major bioactive polyphenolic ingredient of turmeric. Increasing evidence
indicates that the health benefits of curcumin are mediated through its anti-inflammatory and …

Curcumin, an active component of turmeric (Curcuma longa), and its effects on health

B Kocaadam, N Şanlier - Critical reviews in food science and …, 2017 - Taylor & Francis
Turmeric (Curcuma longa) is a type of herb belonging to ginger family, which is widely
grown in southern and south western tropical Asia region. Turmeric, which has an …

Curcumin-loaded nanoparticles: A novel therapeutic strategy in treatment of central nervous system disorders

H Yavarpour-Bali, M Ghasemi-Kasman… - International journal of …, 2019 - Taylor & Francis
Curcumin as a hydrophobic polyphenol is extracted from the rhizome of Curcuma longa.
Curcumin is widely used as a dietary spice and a topical medication for the treatment of …

Liposomal curcumin and its application in cancer

T Feng, Y Wei, RJ Lee, L Zhao - International journal of …, 2017 - Taylor & Francis
Curcumin (CUR) is a yellow polyphenolic compound derived from the plant turmeric. It is
widely used to treat many types of diseases, including cancers such as those of lung …

A review of therapeutic potentials of turmeric (Curcuma longa) and its active constituent, curcumin, on inflammatory disorders, pain, and their related patents

BM Razavi, M Ghasemzadeh Rahbardar… - Phytotherapy …, 2021 - Wiley Online Library
Turmeric (Curcuma longa) and its constituent, curcumin, have been used for their
therapeutic properties for a long time. Most of the medicinal impacts of turmeric and …

Curcumin as an anti‐inflammatory agent: Implications to radiotherapy and chemotherapy

B Farhood, K Mortezaee, NH Goradel… - Journal of cellular …, 2019 - Wiley Online Library
Cancer is the second cause of death worldwide. Chemotherapy and radiotherapy are the
most common modalities for the treatment of cancer. Experimental studies have shown that …

Curcumin, inflammation, and chronic diseases: how are they linked?

Y He, Y Yue, X Zheng, K Zhang, S Chen, Z Du - Molecules, 2015 - mdpi.com
It is extensively verified that continued oxidative stress and oxidative damage may lead to
chronic inflammation, which in turn can mediate most chronic diseases including cancer …

Is curcumin bioavailability a problem in humans: Lessons from clinical trials

AB Kunnumakkara, C Harsha, K Banik… - Expert opinion on …, 2019 - Taylor & Francis
Introduction: Since ancient times, turmeric has been used in several folklore remedies
against various ailments. The principal component of turmeric is curcumin and its efficacy …

The mechanism of NLRP3 inflammasome activation and its pharmacological inhibitors

X Zhan, Q Li, G Xu, X Xiao, Z Bai - Frontiers in Immunology, 2023 - frontiersin.org
NLRP3 (NOD-, LRR-, and pyrin domain-containing protein 3) is a cytosolic pattern
recognition receptor (PRR) that recognizes multiple pathogen-associated molecular patterns …

Antioxidant and anti-inflammatory effects of curcuminoid-piperine combination in subjects with metabolic syndrome: a randomized controlled trial and an updated …

Y Panahi, MS Hosseini, N Khalili, E Naimi, M Majeed… - Clinical nutrition, 2015 - Elsevier
Background Oxidative stress and inflammation have been proposed as emerging
components of metabolic syndrome (MetS). Curcuminoids are natural polyphenols with …