Macrophages undergo profound metabolic reprogramming upon sensing infectious and
sterile stimuli. This metabolic shift supports and regulates essential innate immune functions …

Despite all the advances of modern medicine, atherosclerosis continues to be one of the
most important medical and social problems. Atherosclerosis is the cause of several …

In most eukaryotic cells, fatty acid synthesis (FAS) occurs in the cytoplasm and in
mitochondria. However, the relative contribution of mitochondrial FAS (mtFAS) to the cellular …

Simple Summary Due to the broad functions of Toll-like receptor 2 (TLR2) in innate
immunity, the drive for the development of TLR2-targeted therapeutic treatments has …

Glycolipids with TLR4 agonistic properties can serve either as therapeutic agents or as
vaccine adjuvants by stimulating the development of proinflammatory responses …

Clonorchis sinensis (C. sinensis) infection induces severe hepatobiliary injuries, which can
cause inflammation, periductal fibrosis, and even cholangiocarcinoma. Sphingolipid …

Few studies have examined the relationship between lipid metabolism and kidney stone
formation, particularly the role of key lipid regulatory factors in kidney stone formation. We …

Over-nourishment or an unbalanced diet has been linked to an increase in the prevalence of
metabolic syndrome. An imbalance in glucolipid metabolism is a major cause of metabolic …

Diabetes mellitus (DM) is a metabolic disorder, which if not managed properly, can lead to
serious health problems over time and impose significant financial burden on the patient …

Sepsis is recognized as a potentially fatal condition characterized by acute organ
dysfunction resulting from an imbalanced immune response to infection. Acute liver injury …