Extracellular vesicles: novel mediators of cell communication in metabolic disease
Metabolic homeostasis emerges from the complex, multidirectional crosstalk between key
metabolic tissues including adipose tissue, liver, and skeletal muscle. This crosstalk …
metabolic tissues including adipose tissue, liver, and skeletal muscle. This crosstalk …
Focus on extracellular vesicles: new frontiers of cell-to-cell communication in cancer
C Ciardiello, L Cavallini, C Spinelli, J Yang… - International journal of …, 2016 - mdpi.com
Extracellular Vesicles (EVs) have received considerable attention in recent years, both as
mediators of intercellular communication pathways that lead to tumor progression, and as …
mediators of intercellular communication pathways that lead to tumor progression, and as …
Exosomes as new players in metabolic organ cross‐talk
C Guay, R Regazzi - Diabetes, Obesity and Metabolism, 2017 - Wiley Online Library
Blood glucose homeostasis requires a constant communication between insulin‐secreting
and insulin‐sensitive cells. A wide variety of circulating factors, including hormones …
and insulin‐sensitive cells. A wide variety of circulating factors, including hormones …
Lymphocyte-derived exosomal microRNAs promote pancreatic β cell death and may contribute to type 1 diabetes development
Type 1 diabetes is an autoimmune disease initiated by the invasion of pancreatic islets by
immune cells that selectively kill the β cells. We found that rodent and human T lymphocytes …
immune cells that selectively kill the β cells. We found that rodent and human T lymphocytes …
[HTML][HTML] Adipocyte-derived extracellular vesicles regulate survival and function of pancreatic β cells
I Gesmundo, B Pardini, E Gargantini, G Gamba… - JCI insight, 2021 - ncbi.nlm.nih.gov
Extracellular vesicles (EVs) are implicated in the crosstalk between adipocytes and other
metabolic organs, and an altered biological cargo has been observed in EVs from human …
metabolic organs, and an altered biological cargo has been observed in EVs from human …
Plasma-derived exosome characterization reveals a distinct microRNA signature in long duration Type 1 diabetes
M Garcia-Contreras, SH Shah, A Tamayo… - Scientific reports, 2017 - nature.com
Type 1 diabetes mellitus (T1DM) results from an autoimmune attack against the insulin-
producing ß cells which leads to chronic hyperglycemia. Exosomes are lipid vesicles …
producing ß cells which leads to chronic hyperglycemia. Exosomes are lipid vesicles …
Extracellular vesicles: mechanisms in human health and disease
M Malloci, L Perdomo, M Veerasamy… - Antioxidants & redox …, 2019 - liebertpub.com
Abstract Significance: Secreted extracellular vesicles (EVs) are now considered veritable
entities for diagnosis, prognosis, and therapeutics. These structures are able to interact with …
entities for diagnosis, prognosis, and therapeutics. These structures are able to interact with …
[HTML][HTML] Extracellular vesicle-shuttled miRNAs: a critical appraisal of their potential as nano-diagnostics and nano-therapeutics in type 2 diabetes mellitus and its …
F Prattichizzo, G Matacchione, A Giuliani… - Theranostics, 2021 - ncbi.nlm.nih.gov
Type 2 diabetes mellitus (T2DM) is a complex multifactorial disease causing the
development of a large range of cardiovascular (CV) complications. Lifestyle changes and …
development of a large range of cardiovascular (CV) complications. Lifestyle changes and …
Exosomes and diabetes
C Castaño, A Novials, M Párrizas - … /metabolism research and …, 2019 - Wiley Online Library
Diabetes is a group of metabolic diseases characterized by elevated blood glucose levels
that drive the development of life‐threatening complications. Diabetes results from a …
that drive the development of life‐threatening complications. Diabetes results from a …
Horizontal transfer of exosomal microRNAs transduce apoptotic signals between pancreatic beta-cells
C Guay, V Menoud, S Rome, R Regazzi - Cell communication and …, 2015 - Springer
Background Diabetes mellitus is a common metabolic disorder characterized by dysfunction
of insulin-secreting pancreatic beta-cells. MicroRNAs are important regulators of beta-cell …
of insulin-secreting pancreatic beta-cells. MicroRNAs are important regulators of beta-cell …