THE PAST decade has witnessed an upsurge in our understanding of the hypothalamic
regulation of appetite. Expression of appetite or the motivational drive toward an energy …

Behavioral phenotyping of transgenic and knockout mice requires rigorous, formal analyses.
Well-characterized paradigms can be chosen from the established behavioral neuroscience …

Neuropeptides released by hypothalamic neurons play a major role in the regulation of
feeding, acting both within the hypothalamus, and at other appetite regulating centres …

Energy balance is maintained via a homeostatic system involving both the brain and the
periphery. A key component of this system is the hypothalamus. Over the past two decades …

Purpose: To describe and evaluate behavioral models of binge-type eating. Data
identification: Studies were identified using Medline and hand searches of bibliographies of …

Restricting access to high-fat foods is a common strategy utilized to promote health. This
strategy may contribute to episodes of overconsumption, however, when the restricted foods …

Energy homeostasis is accomplished through a highly integrated and redundant
neurohumoral system. Recently, novel molecular mediators and regulatory pathways for …

Galanin inhibits food consumption in satiated rats. Discovered relatively recently, galanin is
a 29-amino-acid neuropeptide, not homologous with any other known peptide. Three G …

Galanin is a 29-amino acid residue neuropeptide, isolated from porcine intestine in 1983 by
Tatemoto coworkers [172], in the laboratory of Viktor Mutt at the Karolinska Institute in …

In this protocol, binge‐type eating is induced in non‐food‐deprived rats by providing limited
access to an optional source of dietary fat: vegetable shortening. The protocol is simple and …