Mycobacterium tuberculosis (Mtb) is the causative agent of tuberculosis, an infectious
disease with one of the highest morbidity and mortality rates worldwide. Leveraging its …

The genome of Mycobacterium tuberculosis, the bacterium responsible for the disease
tuberculosis, contains an unusual family of abundant antigens (PE/PPEs). To date, certain …

Simple Summary Due to the broad functions of Toll-like receptor 2 (TLR2) in innate
immunity, the drive for the development of TLR2-targeted therapeutic treatments has …

To the PE_PGRS protein subfamily belongs a group of surface-exposed mycobacterial
antigens that in Mycobacterium tuberculosis (Mtb) H37Rv accounts to more than 65 genes …

Autophagy is an ubiquitous homeostatic pathway in mammalian cells and plays a significant
role in host immunity. Substantial evidence indicates that the ability of Mycobacterium …

Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), is one of the most grievous
infectious diseases with long-term morbidity and unpredicted mortality rates globally. Thus …

Mycobacterium tuberculosis (Mtb) modulates diverse cell death pathways to escape the host
immune responses and favor its dissemination, a complex process of interest in …

Mycobacterium tuberculosis has thrived in parallel with humans for millennia, and despite
our efforts, M. tuberculosis continues to plague us, currently infecting a third of the world's …

Despite representing a very important class of virulence proteins, the role of lipoproteins in
the pathogenesis of Mycobacterium tuberculosis remains elusive. In this study, we …

Many key insights into actin regulation have been derived through examining how microbial
pathogens intercept the actin cytoskeleton during infection. Mycobacterium marinum, a close …