Infectious diseases may affect brain function and cause encephalopathy even when the
pathogen does not directly infect the central nervous system, known as infectious disease …

Acute kidney injury (AKI) is emerging as a complication of increasing clinical importance
associated with substantial morbidity and mortality in African children with severe malaria …

Lactic acidosis and hyperlactatemia are common metabolic disturbances in patients with
severe malaria. Lactic acidosis causes physiological adverse effects, which can aggravate …

Infections with Plasmodium falciparum and Plasmodium vivax cause over 600,000 deaths
each year, concentrated in Africa and in young children, but much of the world's population …

Hypertension affects over a billion adults worldwide and is one of the leading causes of
premature death. 1 In younger children, most hypertension is secondary but primary …

Background Globally, 85% of acute kidney injury (AKI) cases occur in low-and-middle-
income countries. There is limited information on persistent kidney disease (acute kidney …

Acute kidney injury (AKI) is a common feature of severe malaria, and an independent risk
factor for death. Previous research has suggested that an overactivation of the host …

Background Under-five mortality remains concentrated in resource-poor countries. Post-
discharge mortality is becoming increasingly recognized as a significant contributor to …

Globally, there are an estimated 13.3 million cases of acute kidney injury (AKI) annually.
Although infections are a common cause of AKI globally, most infection-associated AKI …

In adults, more deficits in physical than mental health domains are found in survivors of AKI
in critical care, whereas memory deficits and learning impairments have been noted in …