[HTML][HTML] Cancer burden in China: trends, risk factors and prevention

D Sun, H Li, M Cao, S He, L Lei, J Peng… - Cancer Biology & …, 2020 - ncbi.nlm.nih.gov
As the most populous country in the world, China has made strides in health promotion in
the past few decades. With the aging population, the burden of cancer in China continues to …

[HTML][HTML] HPV16 and HPV18 genome structure, expression, and post-transcriptional regulation

L Yu, V Majerciak, ZM Zheng - International journal of molecular sciences, 2022 - mdpi.com
Human papillomaviruses (HPV) are a group of small non-enveloped DNA viruses whose
infection causes benign tumors or cancers. HPV16 and HPV18, the two most common high …

Human papillomavirus testing in head and neck carcinomas: guideline from the College of American Pathologists

JS Lewis Jr, B Beadle, JA Bishop… - … of pathology & …, 2018 - meridian.allenpress.com
Context Human papillomavirus (HPV) is a major cause of oropharyngeal squamous cell
carcinomas, and HPV (and/or surrogate marker p16) status has emerged as a prognostic …

DNA tumor virus oncogenes antagonize the cGAS-STING DNA-sensing pathway

L Lau, EE Gray, RL Brunette, DB Stetson - Science, 2015 - science.org
Cyclic guanosine monophosphate–adenosine monophosphate synthase (cGAS) detects
intracellular DNA and signals through the adapter protein STING to initiate the antiviral …

Bacterial infections and cancer

D van Elsland, J Neefjes - EMBO reports, 2018 - embopress.org
Infections are estimated to contribute to 20% of all human tumours. These are mainly caused
by viruses, which explains why a direct bacterial contribution to cancer formation has been …

[HTML][HTML] The human papillomavirus (HPV)-related cancer biology: An overview

RP Araldi, TA Sant'Ana, DG Módolo, TC de Melo… - Biomedicine & …, 2018 - Elsevier
Despite the novel diagnostic methods and therapies implemented in oncology, the number
of patients that succumb by the cancer remains high globally. Currently studies point out that …

International Cancer Microbiome Consortium consensus statement on the role of the human microbiome in carcinogenesis

AJ Scott, JL Alexander, CA Merrifield, D Cunningham… - Gut, 2019 - gut.bmj.com
Objective In this consensus statement, an international panel of experts deliver their
opinions on key questions regarding the contribution of the human microbiome to …

HPV in the etiology of human cancer

N Muñoz, X Castellsagué, AB de González… - Vaccine, 2006 - Elsevier
The causal role of human papillomavirus (HPV) in all cancers of the uterine cervix has been
firmly established biologically and epidemiologically. Most cancers of the vagina and anus …

Lost in transcription: p21 repression, mechanisms, and consequences

AL Gartel, SK Radhakrishnan - Cancer research, 2005 - AACR
The cyclin-dependent kinase inhibitor p21WAF1/CIP1 is a major player in cell cycle control
and it is mainly regulated at the transcriptional level. Whereas induction of p21 …

Molecular transitions from papillomavirus infection to cervical precancer and cancer: Role of stromal estrogen receptor signaling

JA Den Boon, D Pyeon, SS Wang… - Proceedings of the …, 2015 - National Acad Sciences
To study the multistep process of cervical cancer development, we analyzed 128 frozen
cervical samples spanning normalcy, increasingly severe cervical intraepithelial neoplasia …