Gaucher disease (GD, ORPHA355) is a rare, autosomal recessive genetic disorder. It is
caused by a deficiency of the lysosomal enzyme, glucocerebrosidase, which leads to an …

Connective tissue disease (CTD) related interstitial lung disease (CTD-ILD) is one of the
leading causes of morbidity and mortality of CTD. Clinically, CTD-ILD is highly heterogenous …

Biomarkers have the potential to become central to the clinical evaluation and monitoring of
patients with chronic fibrosing interstitial lung diseases (ILDs) with a progressive phenotype …

Rheumatoid arthritis (RA) is a systemic autoimmune disease affecting 0.5–1% of the
worldwide population. Whilst predominantly causing chronic pain and inflammation in …

Lung involvement, especially interstitial lung disease, is a potentially severe extra-glandular
manifestation of Primary Sjogren's Syndrome (pSS-ILD). ILD can manifest either as a late …

Screening and follow-up of interstitial lung disease associated with rheumatoid arthritis (RA-
ILD) is a challenge in clinical practice. In fact, the majority of RA-ILD patients are …

The aim of this study was to determine the role of endothelin-1 (ET-1), a molecule involved
in multiple vascular and fibrosing abnormalities, as a biomarker of interstitial lung disease …

Disease behaviour in interstitial lung disease (ILD) is highly variable and accurate clinical
tools to predict prognosis and guide management decisions remain unsatisfactorily elusive …

It was aimed to evaluate KL-6 glycoprotein levels to determine if it may be a diagnostic
marker for the connective tissue diseases (CTDs) predicting CTD-related interstitial lung …

Interstitial lung disease (ILD) is commonly present in patients with an underlying connective
tissue disease (CTD), particularly those with systemic sclerosis, rheumatoid arthritis, and …