[HTML][HTML] The role of Na/K-ATPase signaling in oxidative stress related to obesity and cardiovascular disease

K Srikanthan, JI Shapiro, K Sodhi - Molecules, 2016 - mdpi.com
Na/K-ATPase has been extensively studied for its ion pumping function, but, in the past
several decades, has been identified as a scaffolding and signaling protein. Initially it was …

Dysfunction of mitochondrial respiratory chain complex I in human failing myocardium is not due to disturbed mitochondrial gene expression

RJ Scheubel, M Tostlebe, A Simm, S Rohrbach… - Journal of the American …, 2002 - jacc.org
Objectives: Activity of mitochondrial respiratory chain complexes with and without
mitochondrially encoded subunits was assessed in failing human myocardium together with …

Xanthine oxidase inhibitor allopurinol prevents oxidative stress‐mediated atrial remodeling in alloxan‐induced diabetes mellitus rabbits

Y Yang, J Zhao, J Qiu, J Li, X Liang… - Journal of the …, 2018 - Am Heart Assoc
Background There are several mechanisms, including inflammation, oxidative stress and
abnormal calcium homeostasis, involved in the pathogenesis of atrial fibrillation. In diabetes …

The effect of xanthine oxidase inhibition upon ejection fraction in heart failure patients: La Plata Study

HE Cingolani, JA Plastino, EM Escudero… - Journal of cardiac …, 2006 - Elsevier
BACKGROUND: Reactive oxygen species (ROS) have been linked to hypertrophy,
remodeling and abnormal excitation-contraction coupling. Previous data demonstrated that …

ROS and RNS signaling in heart disorders: could antioxidant treatment be successful?

I Afanas′ ev - Oxidative medicine and cellular longevity, 2011 - Wiley Online Library
There is not too much success in the antioxidant treatment of heart deceases in humans.
However a new approach is now developed that suggests that depending on their structures …

Cardioprotective effects of curcumin

S Miriyala, M Panchatcharam… - The molecular targets and …, 2007 - Springer
Curcumin, a major active component of turmeric, is extracted from the powdered dry rhizome
of Curcuma longa Linn (Zingiberaceae) and it has been used for centuries in indigenous …

Role of oxidative stress in cardiac remodelling after myocardial infarction

DJ Grieve, JA Byrne, AC Cave, AM Shah - Heart, Lung and Circulation, 2004 - Elsevier
Recovery from myocardial infarction is associated with a series of alterations in heart
structure and function, collectively known as cardiac remodelling, which play a major role in …

Xanthine oxidoreductase: a journey from purine metabolism to cardiovascular excitation-contraction coupling

A Agarwal, A Banerjee, UC Banerjee - Critical reviews in …, 2011 - Taylor & Francis
Xanthine oxidoreductase (XOR) is a ubiquitous complex cytosolic molybdoflavoprotein
which controls the rate limiting step of purine catabolism by converting xanthine to uric acid …

Oxidative and nitrosative stress in the maintenance of myocardial function

Y Zhang, CG Tocchetti, T Krieg, AL Moens - Free Radical Biology and …, 2012 - Elsevier
Reactive oxygen species (ROS) are generated by several different cellular sources, and
their accumulation within the myocardium is widely considered to cause harmful oxidative …

Chronic treatment with allopurinol boosts survival and cardiac contractility in murine postischemic cardiomyopathy

LB Stull, MK Leppo, L Szweda, WD Gao… - Circulation …, 2004 - Am Heart Assoc
Oxidative stress is a hallmark of systemic illnesses, including heart failure. Nevertheless, the
overall importance of radical production in the heart remains conjectural; is it merely a …