Oxidative stress and myocardial injury in the diabetic heart
DM Ansley, B Wang - The Journal of pathology, 2013 - Wiley Online Library
Reactive oxygen or nitrogen species play an integral role in both myocardial injury and
repair. This dichotomy is differentiated at the level of species type, amount and duration of …
repair. This dichotomy is differentiated at the level of species type, amount and duration of …
Myocardial stress and autophagy: mechanisms and potential therapies
LMD Delbridge, KM Mellor, DJ Taylor… - Nature Reviews …, 2017 - nature.com
Autophagy is a ubiquitous cellular catabolic process responsive to energy stress. Research
over the past decade has revealed that cardiomyocyte autophagy is a prominent …
over the past decade has revealed that cardiomyocyte autophagy is a prominent …
Autophagic adaptations in diabetic cardiomyopathy differ between type 1 and type 2 diabetes
H Kanamori, G Takemura, K Goto, A Tsujimoto… - Autophagy, 2015 - Taylor & Francis
Little is known about the association between autophagy and diabetic cardiomyopathy. Also
unknown are possible distinguishing features of cardiac autophagy in type 1 and type 2 …
unknown are possible distinguishing features of cardiac autophagy in type 1 and type 2 …
Glucagon-like peptide-1 protects against cardiac microvascular injury in diabetes via a cAMP/PKA/Rho-dependent mechanism
D Wang, P Luo, Y Wang, W Li, C Wang, D Sun… - Diabetes, 2013 - Am Diabetes Assoc
Impaired cardiac microvascular function contributes to cardiovascular complications in
diabetes. Glucagon-like peptide-1 (GLP-1) exhibits potential cardioprotective properties in …
diabetes. Glucagon-like peptide-1 (GLP-1) exhibits potential cardioprotective properties in …
[HTML][HTML] Metformin attenuates postinfarction myocardial fibrosis and inflammation in mice
Diabetes is a major risk factor for the development of cardiovascular disease with a higher
incidence of myocardial infarction. This study explores the role of metformin, a first-line …
incidence of myocardial infarction. This study explores the role of metformin, a first-line …
[HTML][HTML] Bone marrow progenitor cell therapy-mediated paracrine regulation of cardiac miRNA-155 modulates fibrotic response in diabetic hearts
Diabetes is associated with a higher incidence of myocardial infarction (MI) and increased
risk for adverse vascular and fibrogenic events post-MI. Bone marrow-derived progenitor cell …
risk for adverse vascular and fibrogenic events post-MI. Bone marrow-derived progenitor cell …
[HTML][HTML] AMPK contributes to cardioprotective effects of pterostilbene against myocardial ischemia-reperfusion injury in diabetic rats by suppressing cardiac oxidative …
Background/Aims: Pterostilbene (PT) exerts antidiabetic effects by decreasing blood glucose
and modulating lipid metabolism and has been shown to attenuate myocardial ischemia …
and modulating lipid metabolism and has been shown to attenuate myocardial ischemia …
[HTML][HTML] (-)-Epigallocatechin-3-gallate attenuates myocardial injury induced by ischemia/reperfusion in diabetic rats and in H9c2 cells under hyperglycemic conditions
Y Wu, ZY Xia, B Zhao, Y Leng… - International …, 2017 - spandidos-publications.com
Epigallocatechin gallate (EGCG) exerts multiple beneficial effects on cardiovascular
performance. In this study, we aimed to examine the effects of EGCG on diabetic …
performance. In this study, we aimed to examine the effects of EGCG on diabetic …
Myocardial autophagic energy stress responses—macroautophagy, mitophagy, and glycophagy
LMD Delbridge, KM Mellor… - American Journal of …, 2015 - journals.physiology.org
An understanding of the role of autophagic processes in the management of cardiac
metabolic stress responses is advancing rapidly and progressing beyond a …
metabolic stress responses is advancing rapidly and progressing beyond a …
[HTML][HTML] 8-Gingerol Ameliorates Myocardial Fibrosis by Attenuating Reactive Oxygen Species, Apoptosis, and Autophagy via the PI3K/Akt/mTOR Signaling Pathway
Y Xue, M Zhang, M Liu, Y Liu, L Li, X Han… - Frontiers in …, 2021 - frontiersin.org
8-gingerol (8-Gin) is the series of phenolic substance that is extracted from ginger. Although
many studies have revealed that 8-Gin has multiple pharmacological properties, the …
many studies have revealed that 8-Gin has multiple pharmacological properties, the …