Natural killer (NK) cells are critical effectors of antiviral immunity. Researchers have
therefore sought to characterize the NK cell response to coronavirus disease 2019 (COVID …

Immune responses to pathogens are complex and not well understood in many diseases,
and this is especially true for infections by persistent pathogens. One mechanism that allows …

Exhaustion of cytotoxic effector natural killer (NK) and CD8+ T cells have important functions
in the establishment of persistent viral infections, but how exhaustion is induced during …

The liver is a complex organ with critical physiological functions including metabolism,
glucose storage, and drug detoxification. Its unique immune profile with large numbers of …

The microRNA, miR-155 regulates both adaptive and innate immune responses. In viral
infections, miR-155 can affect both innate immunity (interferon response, natural killer cell …

The hepatitis C virus (HCV) causes both acute and chronic infection and continues to be a
global problem despite advances in antiviral therapeutics. Current treatments fail to prevent …

Abstract The World Health Organization estimates that 71 million people worldwide have
chronic hepatitis C viral infection. A major challenge is overall lack of public awareness of …

Influenza A virus (IAV) is a major global public health burden due to its routine evasion of
immunization strategies. Natural killer (NK) cells are innate cytotoxic cells with important …

Hepatocellular carcinoma (HCC) is currently the third leading cause of malignancy-related
mortalities worldwide. Natural killer (NK) cells are involved in the critical role of first line …

Many maternal immune cells populate the decidua, which is the mucosal lining of the uterus
transformed during pregnancy. Here, abundant natural killer (NK) cells and macrophages …