The incompletely fulfilled promise of embryo transfer in cattle—why aren't pregnancy rates greater and what can we do about it?
PJ Hansen - Journal of Animal Science, 2020 - academic.oup.com
Typically, bovine embryos are transferred into recipient females about day 7 after estrus or
anticipated ovulation, when the embryo has reached the blastocyst stage of development …
anticipated ovulation, when the embryo has reached the blastocyst stage of development …
Strategies for modelling endometrial diseases
AR Murphy, H Campo, JJ Kim - Nature Reviews Endocrinology, 2022 - nature.com
Each month during a woman's reproductive years, the endometrium undergoes vast
changes to prepare for a potential pregnancy. Diseases of the endometrium arise for …
changes to prepare for a potential pregnancy. Diseases of the endometrium arise for …
[HTML][HTML] Future regenerative medicine developments and their therapeutic applications
Although the currently available pharmacological assays can cure most pathological
disorders, they have limited therapeutic value in relieving certain disorders like myocardial …
disorders, they have limited therapeutic value in relieving certain disorders like myocardial …
Generation of offspring-producing 3D ovarian organoids derived from female germline stem cells and their application in toxicological detection
X Li, M Zheng, B Xu, D Li, Y Shen, Y Nie, L Ma, J Wu - Biomaterials, 2021 - Elsevier
In vitro production of oocytes capable of producing offspring has exciting potential
applications in reproductive medicine. Here, we generated and characterized an ovarian …
applications in reproductive medicine. Here, we generated and characterized an ovarian …
Novel microarchitecture of human endometrial glands: implications in endometrial regeneration and pathologies
N Tempest, CJ Hill, A Maclean… - Human …, 2022 - academic.oup.com
BACKGROUND Human endometrium remains a poorly understood tissue of the female
reproductive tract. The superficial endometrial functionalis, the site of embryo implantation, is …
reproductive tract. The superficial endometrial functionalis, the site of embryo implantation, is …
Capture and metabolomic analysis of the human endometrial epithelial organoid secretome
CA Simintiras, P Dhakal, C Ranjit… - Proceedings of the …, 2021 - National Acad Sciences
Suboptimal uterine fluid (UF) composition can lead to pregnancy loss and likely contributes
to offspring susceptibility to chronic adult-onset disorders. However, our understanding of …
to offspring susceptibility to chronic adult-onset disorders. However, our understanding of …
Human organoid systems in modeling reproductive tissue development, function, and disease
S Haider, AG Beristain - Human Reproduction, 2023 - academic.oup.com
Research focused on human reproductive biology has primarily relied upon clinical samples
affording mainly descriptive studies with limited implementation of functional or mechanistic …
affording mainly descriptive studies with limited implementation of functional or mechanistic …
[HTML][HTML] Biomaterial strategies for the application of reproductive tissue engineering
Human reproductive organs are of vital importance to the life of an individual and the
reproduction of human populations. So far, traditional methods have a limited effect in …
reproduction of human populations. So far, traditional methods have a limited effect in …
[HTML][HTML] Collagen I triggers directional migration, invasion and matrix remodeling of stroma cells in a 3D spheroid model of endometriosis
A Stejskalová, V Fincke, M Nowak, Y Schmidt… - Scientific reports, 2021 - nature.com
Endometriosis is a painful gynecological condition characterized by ectopic growth of
endometrial cells. Little is known about its pathogenesis, which is partially due to a lack of …
endometrial cells. Little is known about its pathogenesis, which is partially due to a lack of …
[HTML][HTML] The role of BMP signaling in female reproductive system development and function
E Magro-Lopez, MÁ Muñoz-Fernández - International journal of molecular …, 2021 - mdpi.com
Bone morphogenetic proteins (BMPs) are a group of multifunctional growth factors that
belong to the transforming growth factor-β (TGF-β) superfamily of proteins. Originally …
belong to the transforming growth factor-β (TGF-β) superfamily of proteins. Originally …