Acute myocardial infarction (MI) is a major cause of death and disability worldwide. In
patients with MI, the treatment of choice for reducing acute myocardial ischemic injury and …

Obstructive disease of the epicardial coronary arteries was recognized as the cause of
angina pectoris> 2 centuries ago, and sudden thrombotic occlusion of an epicardial …

The blood‐brain barrier (BBB), as a crucial gate of brain‐blood molecular exchange, is
involved in the pathogenesis of multiple neurological diseases. Oxidative stress is caused …

Document Reviewers: Sigmund Silber (CPG Review Coordinator)(Germany), Frank V.
Aguirre (USA), Nawwar Al-Attar (France), Eduardo Alegria (Spain), Felicita Andreotti (Italy) …

appeared to plug the capillary lumen. 13 Cellular edema compressing the capillaries was
confirmed in more than one experiment. 10, 21, 22 This may explain the occasional benefit …

OBJECTIVES We sought to elucidate the long-term prognostic importance of angiographic
no-reflow phenomenon after percutaneous transluminal coronary angioplasty (PTCA) for …

The phenomenon of no-reflow is defined as inadequate myocardial perfusion through a
given segment of the coronary circulation without angiographic evidence of mechanical …

Successful restoration of epicardial coronary artery patency after prolonged occlusion might
result in microvascular obstruction (MVO) and is observed both experimentally as well as …

To achieve early and complete reperfusion of the myocardium in acute coronary syndromes
is the daily challenge for every physician in clinical cardiology. However, restoration of …

Background—The benefits of vessel recanalization in acute myocardial infarction (AMI) are
limited by reperfusion damage. In animal models, adenosine limits reperfusion injury …