Rationale: GLP-1R (glucagon-like peptide-1 receptor) agonists are approved to treat type 2
diabetes mellitus and obesity. GLP-1R agonists reduce airway inflammation and …

Background Electronic medical records (EMRs) contain large amounts of rich clinical
information. Developing EMR-based case definitions, also known as EMR phenotyping, is …

Objective In health informatics, there have been concerns with reuse of electronic health
data for research, including potential bias from incorrect or incomplete outcome …

Introduction The association between allergic diseases and autoimmune disorders is not
well established. Our objective was to determine incidence rates of autoimmune disorders in …

Background Diabetes is associated with worse asthma morbidity. Metformin, which treats
diabetes, may have a role among patients with asthma and glycemic dysfunction. Objective …

Background Electronic health record (EHR) databases can facilitate epidemiology research
into various diseases including asthma. Given the diagnostic challenges of asthma, the …

Purpose Standardized approaches for rigorous validation of phenotyping from large-scale
electronic health record (EHR) data have not been widely reported. We proposed a …

Objectives To determine the incidence of osteoarthrits (OA) in patients with atopic disease
compared with matched non-exposed patients. Methods We conducted a retrospective …

Objective To investigate the impact on child health up to age 5 years of a policy to use
antibiotic prophylaxis for caesarean section before incision compared with after cord …

Background Viable knowledge translation (KT) strategies are increasingly sought to improve
asthma diagnosis, particularly in primary care. Despite this understanding, practical KT tools …