Coronaviruses can cause serious respiratory tract infections and may also impact other end
organs such as the central nervous system, the lung and the heart. The coronavirus disease …

Infectious diseases have been a threat to human health globally. The relentless efforts and
research have enabled us to overcome most of the diseases through the use of antiviral and …

Inflammation and oxidative stress represent physiological response mechanisms to different
types of stimuli and injury during critical illness. Its proper regulation is fundamental to …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection causes
coronavirus disease 2019 (COVID-19) and can be associated with serious complications …

The aim of this study was to evaluate the effect and safety of N‐acetylcysteine (NAC)
inhalation spray in the treatment of patients with coronavirus disease 2019 (COVID‐19). This …

In SARS-CoV-2-infected humans, disease progression is often associated with acute
respiratory distress syndrome involving severe lung injury, coagulopathy, and thrombosis of …

Background Endotheliopathy and coagulopathy appear to be the main causes for critical
illness and death in patients with coronavirus disease 2019 (COVID-19). The adhesive …

Inflammasome activation is one of the first steps in initiating innate immune responses. In
this work, we studied the activation of inflammasomes in the airways of critically ill COVID-19 …

Objectives: Recent clinical studies suggest that oxidative stress is one of the key players in
the pathogenesis of coronavirus disease 2019 (COVID-19), and N-acetylcysteine (NAC), a …

The coronavirus disease (COVID-19) pandemic is a leading global health and economic
challenge. What defines the disease's progression is not entirely understood, but there are …