Microbial biofilm: formation, architecture, antibiotic resistance, and control strategies

MA Rather, K Gupta, M Mandal - Brazilian Journal of Microbiology, 2021 - Springer
The assembly of microorganisms over a surface and their ability to develop resistance
against available antibiotics are major concerns of interest. To survive against harsh …

Targeting the holy triangle of quorum sensing, biofilm formation, and antibiotic resistance in pathogenic bacteria

RV Sionov, D Steinberg - Microorganisms, 2022 - mdpi.com
Chronic and recurrent bacterial infections are frequently associated with the formation of
biofilms on biotic or abiotic materials that are composed of mono-or multi-species cultures of …

Antibiotic resistance in Pseudomonas aeruginosa–Mechanisms, epidemiology and evolution

J Botelho, F Grosso, L Peixe - Drug resistance updates, 2019 - Elsevier
Antibiotics are powerful drugs used in the treatment of bacterial infections. The inappropriate
use of these medicines has driven the dissemination of antibiotic resistance (AR) in most …

Microbial surface colonization and biofilm development in marine environments

H Dang, CR Lovell - Microbiology and molecular biology reviews, 2016 - Am Soc Microbiol
Biotic and abiotic surfaces in marine waters are rapidly colonized by microorganisms.
Surface colonization and subsequent biofilm formation and development provide numerous …

Biofilms and cyclic di-GMP (c-di-GMP) signaling: lessons from Pseudomonas aeruginosa and other bacteria

M Valentini, A Filloux - Journal of Biological Chemistry, 2016 - ASBMB
The cyclic di-GMP (c-di-GMP) second messenger represents a signaling system that
regulates many bacterial behaviors and is of key importance for driving the lifestyle switch …

Pseudomonas aeruginosa : new insights into pathogenesis and host defenses

SL Gellatly, REW Hancock - Pathogens and disease, 2013 - academic.oup.com
Pseudomonas aeruginosa is a metabolically versatile bacterium that can cause a wide
range of severe opportunistic infections in patients with serious underlying medical …

Roles of Two-Component Systems in Pseudomonas aeruginosa Virulence

M Sultan, R Arya, KK Kim - International journal of molecular sciences, 2021 - mdpi.com
Pseudomonas aeruginosa is an opportunistic pathogen that synthesizes and secretes a
wide range of virulence factors. P. aeruginosa poses a potential threat to human health …

Advancements in antimicrobial nanoscale materials and self-assembling systems

JA Doolan, GT Williams, KLF Hilton… - Chemical Society …, 2022 - pubs.rsc.org
Antimicrobial resistance is directly responsible for more deaths per year than either
HIV/AIDS or malaria and is predicted to incur a cumulative societal financial burden of at …

Applying insights from biofilm biology to drug development—can a new approach be developed?

T Bjarnsholt, O Ciofu, S Molin, M Givskov… - Nature reviews Drug …, 2013 - nature.com
Most of the research on bacterial pathogenesis has focused on acute infections, but much
less is known about the pathogenesis of infections caused by bacteria that grow as …

Pseudomonas aeruginosa Twitching Motility: Type IV Pili in Action

LL Burrows - Annual review of microbiology, 2012 - annualreviews.org
Type IV pili (T4P) are one of the most common forms of bacterial and archaeal surface
structures, involved in adherence, motility, competence for DNA uptake, and pathogenesis …