Advances in the Science, Treatment, and Prevention of the Disease of Obesity: Reflections From a Diabetes Care Editors' Expert Forum

WT Cefalu, GA Bray, PD Home, WT Garvey… - Diabetes …, 2015 - Am Diabetes Assoc
As obesity rates increase, so too do the risks of type 2 diabetes, cardiovascular disease, and
numerous other detrimental conditions. The prevalence of obesity in US adults more than …

The basis for weekly insulin therapy: evolving evidence with insulin icodec and insulin efsitora alfa

J Rosenstock, R Juneja, JM Beals, JS Moyers… - Endocrine …, 2024 - academic.oup.com
Basal insulin continues to be a vital part of therapy for many people with diabetes. First
attempts to prolong the duration of insulin formulations were through the development of …

American Association of Clinical Endocrinology clinical practice guideline: developing a diabetes mellitus comprehensive care plan—2022 update

L Blonde, GE Umpierrez, SS Reddy, JB McGill… - Endocrine Practice, 2022 - Elsevier
Objective The objective of this clinical practice guideline is to provide updated and new
evidence-based recommendations for the comprehensive care of persons with diabetes …

Efficacy and safety of intermittent fasting in people with insulin-treated type 2 diabetes (INTERFAST-2)—a randomized controlled trial

A Obermayer, NJ Tripolt, PN Pferschy, H Kojzar… - Diabetes …, 2023 - Am Diabetes Assoc
OBJECTIVE To investigate the safety and feasibility of 3 nonconsecutive days of intermittent
fasting (IF) per week over 12 weeks in participants with insulin-treated type 2 diabetes …

Insulin‐associated weight gain in obese type 2 diabetes mellitus patients: What can be done?

A Brown, N Guess, A Dornhorst… - Diabetes, Obesity and …, 2017 - Wiley Online Library
Insulin therapy (IT) is initiated for patients with type 2 diabetes mellitus when glycaemic
targets are not met with diet and other hypoglycaemic agents. The initiation of IT improves …

Reduction in glycated hemoglobin and daily insulin dose alongside circadian clock upregulation in patients with type 2 diabetes consuming a three-meal diet: a …

D Jakubowicz, Z Landau, S Tsameret… - Diabetes …, 2019 - Am Diabetes Assoc
OBJECTIVE In type 2 diabetes, insulin resistance and progressive β-cell failure require
treatment with high insulin doses, leading to weight gain. Our aim was to study whether a …

Toward big data analytics: review of predictive models in management of diabetes and its complications

SL Cichosz, MD Johansen… - Journal of diabetes …, 2016 - journals.sagepub.com
Diabetes is one of the top priorities in medical science and health care management, and an
abundance of data and information is available on these patients. Whether data stem from …

[HTML][HTML] Rationale for timely insulin therapy in type 2 diabetes within the framework of individualised treatment: 2020 update

M Hanefeld, H Fleischmann, T Siegmund, J Seufert - Diabetes Therapy, 2020 - Springer
Type 2 diabetes is characterised by chronic hyperglycaemia and variable degrees of insulin
deficiency and resistance. Hyperglycaemia and elevated fatty acids exert harmful effects on …

[HTML][HTML] Efficacy and safety of canagliflozin in combination with insulin: a double-blind, randomized, placebo-controlled study in Japanese patients with type 2 …

N Inagaki, S Harashima, N Maruyama… - Cardiovascular …, 2016 - Springer
Background Combination therapy with canagliflozin and insulin was investigated in a
prescribed substudy of the canagliflozin Cardiovascular Assessment Study (CANVAS); …

Prevalence and correlation of glycemic control achievement in patients with type 2 diabetes in Iraq: A retrospective analysis of a tertiary care database over a 9-year …

AA Mansour, NTY Alibrahim, HA Alidrisi… - Diabetes & Metabolic …, 2020 - Elsevier
Background This study was designed to assess the achievement of a glycated hemoglobin
(HbA1c) target in Iraqi type 2 diabetes mellitus (T2DM) patients via retrospective analysis of …