Acute lymphoblastic leukaemia (ALL) occurs in approximately 1: 1500 children and is less
frequently found in adults. The most common immunophenotype of ALL is the B cell lineage …

Approximately 15% of pediatric B cell precursor acute lymphoblastic leukemia (BCP-ALL) is
characterized by gene expression similar to that of BCR-ABL1-positive disease and …

Mantle cell lymphoma (MCL) is an uncommon subtype of non-Hodgkin lymphoma occurring
in adults and elderly people with a peculiar male predominance. Genetically, it is …

Minimal residual disease (MRD) monitoring by PCR methods is a strong and standardized
predictor of clinical outcome in mantle cell lymphoma (MCL) and follicular lymphoma (FL) …

BACKGROUND Over 500 translocations have been identified in acute leukemia. To detect
them, most diagnostic laboratories use karyotyping, fluorescent in situ hybridization, and …

DNA testing in patients suspected of having a genetic disorder will not always result in clear
findings. Whereas in some patients changes in their DNA are identified that clearly explain …

Approximately 15% of pediatric B cell precursor acute lymphoblastic leukemia (BCP-ALL) is
characterized by gene expression similar to that of BCR‑ABL1-positive disease and …

There is a large number of patients waiting for cells, tissues and organs for transplantation
worldwide, but the available human donors cannot fill this need. Xenotransplantation might …

In 1865 the Augustinian friar and scientist Gregor Mendel was the first to give a systematic
account of the heredity of traits following specific laws [239]. In the following decades it was …