Targeting angiogenesis in breast cancer: current evidence and future perspectives of novel anti-angiogenic approaches
NM Ayoub, SK Jaradat, KM Al-Shami… - Frontiers in …, 2022 - frontiersin.org
Angiogenesis is a vital process for the growth and dissemination of solid cancers. Numerous
molecular pathways are known to drive angiogenic switch in cancer cells promoting the …
molecular pathways are known to drive angiogenic switch in cancer cells promoting the …
Cyclical endometrial repair and regeneration
Uniquely among adult tissues, the human endometrium undergoes cyclical shedding, scar-
free repair and regeneration during a woman's reproductive life. Therefore, it presents an …
free repair and regeneration during a woman's reproductive life. Therefore, it presents an …
Tumor-derived systems as novel biomedical tools—turning the enemy into an ally
Cancer is a complex illness that presents significant challenges in its understanding and
treatment. The classic definition," a group of diseases characterized by the uncontrolled …
treatment. The classic definition," a group of diseases characterized by the uncontrolled …
[HTML][HTML] Exosomal RNAs in diagnosis and therapies
P Narang, M Shah, V Beljanski - Non-coding RNA Research, 2022 - Elsevier
The field of extracellular vesicles has been rapidly developing after it became evident that a
defined subset of vesicles, called exosomes, can modulate several biological functions in …
defined subset of vesicles, called exosomes, can modulate several biological functions in …
Counter regulation of tumor angiogenesis by vascular endothelial growth factor and thrombospondin-1
J Lawler - Seminars in Cancer Biology, 2022 - Elsevier
Considerable progress has been made in our understanding of the process of angiogenesis
in the context of normal and tumor tissue over the last fifty years. Angiogenesis, like most …
in the context of normal and tumor tissue over the last fifty years. Angiogenesis, like most …
The emerging role of pericyte-derived extracellular vesicles in vascular and neurological health
Pericytes (PCs), as a central component of the neurovascular unit, contribute to the
regenerative potential of the central nervous system (CNS) and peripheral nervous system …
regenerative potential of the central nervous system (CNS) and peripheral nervous system …
Plant extracellular vesicles: A novel bioactive nanoparticle for tumor therapy
ZL Tan, JF Li, HM Luo, YY Liu, Y Jin - Frontiers in Pharmacology, 2022 - frontiersin.org
Extracellular vesicles are tiny lipid bilayer-enclosed membrane particles, including apoptotic
bodies, micro vesicles, and exosomes. Organisms of all life forms can secrete extracellular …
bodies, micro vesicles, and exosomes. Organisms of all life forms can secrete extracellular …
Liquid biopsy in lung cancer: biomarkers for the management of recurrence and metastasis
Liquid biopsies have emerged as a promising tool for the detection of metastases as well as
local and regional recurrence in lung cancer. Liquid biopsy tests involve analyzing a …
local and regional recurrence in lung cancer. Liquid biopsy tests involve analyzing a …
Hypoxic regulation of extracellular vesicles: Implications for cancer therapy
S Yoo, S Choi, I Kim, IS Kim - Journal of Controlled Release, 2023 - Elsevier
Extracellular vesicles (EVs) play a pivotal role in intercellular communication and have been
implicated in cancer progression. Hypoxia, a pervasive hallmark of cancer, is known to …
implicated in cancer progression. Hypoxia, a pervasive hallmark of cancer, is known to …
Role of ATP in extracellular vesicle biogenesis and dynamics
M Lombardi, M Gabrielli, E Adinolfi… - Frontiers in …, 2021 - frontiersin.org
Adenosine triphosphate (ATP) is among the molecules involved in the immune response. It
acts as danger signal that promotes inflammation by activating both P2X and P2Y purinergic …
acts as danger signal that promotes inflammation by activating both P2X and P2Y purinergic …