Background Schizophrenia is a common, severe, and usually chronic disorder. Maintenance
treatment with antipsychotic drugs can prevent relapse but also causes side-effects. We …

Background The symptoms and signs of schizophrenia have been linked to high levels of
dopamine in specific areas of the brain (limbic system). Antipsychotic drugs block the …

According to current evidence and guidelines, continued antipsychotic treatment is key for
preventing relapse in people with schizophrenia‐spectrum disorders, but evidence‐based …

These updated guidelines from the British Association for Psychopharmacology replace the
original version published in 2011. They address the scope and targets of pharmacological …

Objective: This study compared relapse prevention and acceptability of long-acting
injectable (LAI) antipsychotics in the maintenance treatment of adults with nonaffective …

Abstract Long-Acting Injectable Antipsychotics (LAIs) are used to overcome non-compliance
in psychoses, mainly schizophrenia spectrum disorders. We aimed to summarize available …

Objective To quantify the risk and predictors of relapse among individuals with
schizophrenia randomly withdrawn from antipsychotic maintenance treatment. Methods We …

Current guidelines for the treatment of patients with schizophrenia advocate that patients
receive treatment with a long-acting injectable (LAI) antipsychotic medication if they prefer …

Introduction Avoidance of relapse is the main aim of long-term antipsychotic treatment in
schizophrenia, yet how 'relapse'is defined in trials is not well-known. Methods We conducted …

Objective Schizophrenia is a chronic, debilitating psychiatric disorder with a high risk of
relapse. Nonadherence to medication is a significant contributor to poor outcomes. Although …