Global burden of liver disease: 2023 update

H Devarbhavi, SK Asrani, JP Arab, YA Nartey… - Journal of …, 2023 - Elsevier
Liver disease accounts for two million deaths annually and is responsible for 4% of all
deaths (1 out of every 25 deaths worldwide); approximately two-thirds of all liver-related …

Alcohol-associated hepatitis

R Bataller, JP Arab, VH Shah - New England Journal of Medicine, 2022 - Mass Medical Soc
Alcohol-Associated Hepatitis | New England Journal of Medicine Skip to main content The New
England Journal of Medicine homepage Advanced Search SEARCH SPECIALTIES Cardiology …

The intersection between alcohol-related liver disease and nonalcoholic fatty liver disease

LA Díaz, JP Arab, A Louvet, R Bataller… - Nature Reviews …, 2023 - nature.com
Nonalcoholic fatty liver disease (NAFLD) and alcohol-related liver disease (ALD) are the
leading causes of chronic liver disease worldwide. NAFLD and ALD share …

[HTML][HTML] Management of alcohol use disorder in patients with cirrhosis in the setting of liver transplantation

JP Arab, M Izzy, L Leggio, R Bataller… - Nature Reviews …, 2022 - nature.com
The prevalence of alcohol use disorder (AUD) has been steadily increasing over the past
decade. In parallel, alcohol-associated liver disease (ALD) has been increasing at an …

[HTML][HTML] Non-alcoholic fatty liver disease and alcohol-related liver disease: two intertwined entities

F Idalsoaga, AV Kulkarni, OY Mousa, M Arrese… - Frontiers in …, 2020 - frontiersin.org
Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease
worldwide, with a prevalence of 25–30%. Since its first description in 1980, NAFLD has …

Reducing the global burden of alcohol‐associated liver disease: a blueprint for action

SK Asrani, J Mellinger, JP Arab, VH Shah - Hepatology, 2021 - Wiley Online Library
Alcohol‐associated liver disease (ALD) is a major driver of global liver related morbidity and
mortality. There are 2.4 billion drinkers (950 million heavy drinkers) and the lifetime …

[PDF][PDF] An open‐label, dose‐escalation study to assess the safety and efficacy of IL‐22 agonist F‐652 in patients with alcohol‐associated hepatitis

JP Arab, TS Sehrawat, DA Simonetto, VK Verma… - …, 2020 - Wiley Online Library
Background and Aims Interleukin‐22 has beneficial effects on inflammation and impaired
hepatic regeneration that characterize alcohol‐associated hepatitis (AH). F‐652 is a …

Alcohol consumption: medical implications, the liver and beyond

V Meza, J Arnold, LA Díaz… - Alcohol and …, 2022 - academic.oup.com
Alcohol consumption represents a major factor of morbidity and mortality, with a wide range
of adverse medical implications that practically affect every organ system. It is the fifth major …

Efficacy and safety of immunosuppression withdrawal in pediatric liver transplant recipients: moving toward personalized management

S Feng, JC Bucuvalas, GV Mazariegos, JC Magee… - …, 2021 - Wiley Online Library
Background and Aims Tolerance is transplantation's holy grail, as it denotes allograft health
without immunosuppression and its toxicities. Our aim was to determine, among stable long …

[HTML][HTML] Association between public health policies on alcohol and worldwide cancer, liver disease and cardiovascular disease outcomes

LA Díaz, E Fuentes-López, F Idalsoaga, G Ayares… - Journal of …, 2024 - Elsevier
Background & Aims The long-term impact of alcohol-related public health policies (PHPs) on
disease burden is unclear. We aimed to assess the association between alcohol-related …