[HTML][HTML] Whole-genome analysis of carbapenem-resistant Acinetobacter baumannii from clinical isolates in Southern Thailand

A Chukamnerd, K Singkhamanan… - Computational and …, 2022 - Elsevier
The worldwide spread of carbapenem-resistant Acinetobacter baumannii (CRAB) has
become a healthcare challenge for some decades. To understand its molecular …

Outer Membrane Proteins and Efflux Pumps Mediated Multi-Drug Resistance in Salmonella: Rising Threat to Antimicrobial Therapy

SD Akshay, VK Deekshit, J Mohan Raj… - ACS Infectious …, 2023 - ACS Publications
Despite colossal achievements in antibiotic therapy in recent decades, drug-resistant
pathogens have remained a leading cause of death and economic loss globally. One such …

[HTML][HTML] Insight into carbapenem resistance and virulence of Acinetobacter baumannii from a children's medical centre in eastern China

Y Zhu, X Zhang, Y Wang, Y Tao, X Shao, Y Li… - Annals of clinical …, 2022 - Springer
Carbapenem-resistant Acinetobacter baumannii (CRAB) appeared more frequently in
children and caused a great threat to global public health. It is urgent to investigate the …

[HTML][HTML] Combatting resistance: understanding multi-drug resistant pathogens in intensive care units

J Teng, S Imani, A Zhou, Y Zhao, L Du, S Deng… - Biomedicine & …, 2023 - Elsevier
The escalating misuse and excessive utilization of antibiotics have led to the widespread
dissemination of drug-resistant bacteria, posing a significant global healthcare crisis. Of …

Nonadditive functional interactions between ligand-binding sites of the multidrug efflux pump AdeB from Acinetobacter baumannii

IV Leus, SR Roberts, A Trinh, E W. Yu… - Journal of …, 2024 - Am Soc Microbiol
Multidrug efflux is one of the major mechanisms of antibiotic resistance identified in clinical
isolates of the human pathogen Acinetobacter baumannii. The multiple antibiotic resistance …

[PDF][PDF] The respiratory tract microbiome, the pathogen load, and clinical interventions define severity of bacterial pneumonia

AE Pérez-Cobas, C Ginevra, C Rusniok, S Jarraud… - Cell Reports …, 2023 - cell.com
Bacterial pneumonia is a considerable problem worldwide. Here, we follow the inter-
kingdom respiratory tract microbiome (RTM) of a unique cohort of 38 hospitalized patients …

[HTML][HTML] A Short Peptide of Autotransporter Ata Is a Promising Protective Antigen for Vaccination Against Acinetobacter baumannii

P Sun, X Li, C Pan, Z Liu, J Wu, H Wang… - Frontiers in …, 2022 - frontiersin.org
With the emergence of multidrug-resistant strains, Acinetobacter baumannii infection is
becoming a thorny health problem in hospitals. However, there are no licensed vaccines …

[HTML][HTML] Facing resistant bacteria with plant essential oils: Reviewing the oregano case

JO Fimbres-García, M Flores-Sauceda, ED Othon-Díaz… - Antibiotics, 2022 - mdpi.com
Antibiotic resistance is a serious global threat, and the misuse of antibiotics is considered its
main cause. It is characterized by the expression of bacterial defense mechanisms, eg, β …

[HTML][HTML] Current state of knowledge regarding WHO critical priority pathogens: Mechanisms of resistance and proposed solutions through candidates such as …

B Badescu, V Buda, M Romanescu, A Lombrea… - Plants, 2022 - mdpi.com
The rise of multidrug-resistant (MDR) pathogens has become a global health threat and an
economic burden in providing adequate and effective treatment for many infections. This …

[HTML][HTML] Snapshot of phenotypic and molecular virulence and resistance profiles in multidrug-resistant strains isolated in a tertiary hospital in Romania

BS Truşcă, I Gheorghe-Barbu, M Manea, E Ianculescu… - Pathogens, 2023 - mdpi.com
A current major healthcare problem is represented by antibiotic resistance, mainly due to
multidrug resistant (MDR) Gram negative bacilli (GNB), because of their extended spread …