Microbiota medicine: towards clinical revolution

P Gebrayel, C Nicco, S Al Khodor, J Bilinski… - Journal of translational …, 2022 - Springer
The human gastrointestinal tract is inhabited by the largest microbial community within the
human body consisting of trillions of microbes called gut microbiota. The normal flora is the …

Gut microbiome and human health: Exploring how the probiotic genus Lactobacillus modulate immune responses

S Rastogi, A Singh - Frontiers in Pharmacology, 2022 - frontiersin.org
The highest density of microbes resides in human gastrointestinal tract, known as “Gut
microbiome”. Of note, the members of the genus Lactobacillus that belong to phyla …

Paraprobiotics: A new perspective for functional foods and nutraceuticals

RA Siciliano, A Reale, MF Mazzeo, S Morandi, T Silvetti… - Nutrients, 2021 - mdpi.com
Probiotics are live microorganisms that confer health benefits on the host. However, in
recent years, several concerns on their use have been raised. In particular, industrial …

Neurodegenerative and neurodevelopmental diseases and the gut-brain axis: The potential of therapeutic targeting of the microbiome

B Bicknell, A Liebert, T Borody, G Herkes… - International journal of …, 2023 - mdpi.com
The human gut microbiome contains the largest number of bacteria in the body and has the
potential to greatly influence metabolism, not only locally but also systemically. There is an …

The role of probiotics and prebiotics in modulating of the gut-brain axis

F Ansari, M Neshat, H Pourjafar, SM Jafari… - Frontiers in …, 2023 - frontiersin.org
Pro-and prebiotics have been indicated to modulate the gut-brain axis, which have
supportive impacts on central nervous systems, and decrease or control the incidence of …

Probiotics: Potential novel therapeutics for microbiota-gut-brain axis dysfunction across gender and lifespan

S Snigdha, K Ha, P Tsai, TG Dinan, JD Bartos… - Pharmacology & …, 2022 - Elsevier
Probiotics are live microorganisms, which when administered in adequate amounts, present
a health benefit for the host. While the beneficial effects of probiotics on gastrointestinal …

The microbiota-gut-brain axis in health and disease and its implications for translational research

MA Schächtle, SP Rosshart - Frontiers in cellular neuroscience, 2021 - frontiersin.org
Over the past decades, microbiome research has evolved rapidly and became a hot topic in
basic, preclinical and clinical research, for the pharmaceutical industry and for the general …

The microbiota-gut-bone axis and bone health

Y Tu, R Yang, X Xu, X Zhou - Journal of leukocyte biology, 2021 - academic.oup.com
The gastrointestinal tract is colonized by trillions of microorganisms, consisting of bacteria,
fungi, and viruses, known as the “second gene pool” of the human body. In recent years, the …

Role of gut microbiota in neurological disorders and its therapeutic significance

P Tiwari, R Dwivedi, M Bansal, M Tripathi… - Journal of Clinical …, 2023 - mdpi.com
In humans, the gut microbiota (GM) are known to play a significant role in the metabolism of
nutrients and drugs, immunomodulation, and pathogen defense by inhabiting the …

[HTML][HTML] Brain modulation by the gut microbiota: From disease to therapy

S Mitra, R Dash, A Al Nishan, SU Habiba… - Journal of Advanced …, 2023 - Elsevier
Background The gut microbiota (GM) and brain are strongly associated, which significantly
affects neuronal development and disorders. GM-derived metabolites modulate neuronal …