In this tutorial, we provide a broad introduction to the topic of interaction between the effects
of exposures. We discuss interaction on both additive and multiplicative scales using risks …

Background Socioeconomic inequalities in longevity have been found in all European
countries. We aimed to assess which determinants make the largest contribution to these …

Eradicating triple-negative breast cancer (TNBC) resistant to neoadjuvant chemotherapy
(NACT) is a critical unmet clinical need. In this study, patient-derived xenograft (PDX) …

Anthracycline-based chemotherapy is associated with increased subsequent breast cancer
(SBC) risk in female childhood cancer survivors, but the current evidence is insufficient to …

When baseline risk of an outcome varies within a population, the effect of a treatment on that
outcome will vary on at least one scale (eg, additive, multiplicative). This treatment effect …

Objective Patients with SLE have increased morbidity and premature mortality. Whether this
mortality gap has improved in recent years, as in RA, is unknown. Methods We conducted a …

Background Most previous studies that investigated associations of surrounding green, air
pollution or traffic noise with mortality focused on single exposures. Objectives The aim of …

Background Everyday people are exposed to multiple environmental factors, such as
surrounding green, air pollution and traffic noise. These exposures are generally spatially …

Objective Mortality trends of rheumatoid arthritis (RA) are largely unknown over the past
decade when new drugs and management strategies have been adopted to effectively treat …

Objective Gout, the most common inflammatory arthritis, is associated with premature
mortality. Whether this mortality gap has improved over time, as observed in rheumatoid …