Total glucosides of paeony: a review of its phytochemistry, role in autoimmune diseases, and mechanisms of action

H Jiang, J Li, L Wang, S Wang, X Nie, Y Chen… - Journal of …, 2020 - Elsevier
Abstract Ethnopharmacological relevance Paeoniae Radix Alba (PRA, called baishao in
China), the root of Paeonia lactiflora Pall., has shown a rich medicinal value for more than …

A review for the anti-inflammatory effects of paeoniflorin in inflammatory disorders

Q Xin, R Yuan, W Shi, Z Zhu, Y Wang, W Cong - Life Sciences, 2019 - Elsevier
Inflammatory disorders result from abnormal immune response and their incidence has
increased recently. Thus, there is an urgent need to discover new treatments for …

Paeoniflorin suppresses TGF-β mediated epithelial-mesenchymal transition in pulmonary fibrosis through a Smad-dependent pathway

Y Ji, Y Dou, Q Zhao, J Zhang, Y Yang, T Wang… - Acta Pharmacologica …, 2016 - nature.com
Aim: Paeoniflorin has shown to attenuate bleomycin-induced pulmonary fibrosis (PF) in
mice. Because the epithelial-mesenchymal transition (EMT) in type 2 lung endothelial cells …

Traditional Chinese medicine for pulmonary fibrosis therapy: Progress and future prospects

LC Li, LD Kan - Journal of ethnopharmacology, 2017 - Elsevier
Ethnopharmacological relevance Pulmonary fibrosis (PF) is a chronic, debilitating and often
lethal lung disorder. Despite the molecular mechanisms of PF are gradually clear with …

Traditional Chinese medicine integrated responsive microneedles for systemic sclerosis treatment

X Luan, X Zhang, M Nie, Y Zhao - Research, 2023 - spj.science.org
Traditional Chinese medicine, such as Tripterygium wilfordii and Paeonia lactiflora, has
potential values in treating systemic sclerosis (SSc) and other autoimmune diseases, while …

[HTML][HTML] Effects of dietary supplement with a Chinese herbal mixture on growth performance, antioxidant capacity, and gut microbiota in weaned pigs

Q Xu, M Cheng, R Jiang, X Zhao, J Zhu… - Frontiers in Veterinary …, 2022 - frontiersin.org
Weaning stress decreases the growth performance of piglets and is one of the main
concerns of pig industries. Traditional Chinese herbal medicines have been used to reduce …

Pulmonary fibrosis: Therapeutic and mechanistic insights into the role of phytochemicals

SA Hosseini, F Zahedipour, T Sathyapalan… - …, 2021 - Wiley Online Library
Pulmonary fibrosis (PF) is the devastating consequence of various inflammatory diseases of
the lung. PF leads to a reduction of lung function, respiratory failure, and death. Several …

[HTML][HTML] Hesperidin ameliorates bleomycin-induced experimental pulmonary fibrosis via inhibition of TGF-beta1/Smad3/AMPK and IkappaBalpha/NF-kappaB …

Z Zhou, AD Kandhare, AA Kandhare… - EXCLI …, 2019 - ncbi.nlm.nih.gov
Bleomycin (BLM) is a chemotherapeutic agent which is associated with Idiopathic
pulmonary fibrosis (IPF) due to its chronic administration. Hesperidin, a bioflavonoid has …

Therapeutic potential of traditional Chinese medicine for interstitial lung disease

YM Zhou, XR Dong, D Xu, J Tang, YL Cui - Journal of Ethnopharmacology, 2023 - Elsevier
Ethnopharmacological relevance Interstitial lung disease (ILD) is a chronic lung dysfunction
disease with a poor prognosis and poor recovery. The clinically used therapeutic drugs …

The role of natural products in the prevention and treatment of pulmonary fibrosis: A review

L Wang, S Li, Y Yao, W Yin, T Ye - Food & function, 2021 - pubs.rsc.org
Pulmonary fibrosis is an incurable end-stage lung disease and remains a global public
health problem. Although there have been some breakthroughs in understanding the …