Paeoniflorin ameliorates airway inflammation and immune response in ovalbumin induced asthmatic mice: From oxidative stress to autophagy

X Han, S Hu, Q Yang, X Sang, D Tang, G Cao - Phytomedicine, 2022 - Elsevier
Background Asthma characterized by airway remodeling is a multiple pulmonary disease,
which is associated with various physiological processes including inflammation reaction …

Chinese medicine as a therapeutic option for pulmonary fibrosis: clinical efficacies and underlying mechanisms

Y Hao, J Li, L Dan, X Wu, X Xiao, H Yang… - Journal of …, 2023 - Elsevier
Ethnic pharmacological relevance Pulmonary fibrosis (PF) is a fibrotic interstitial lung
disease caused by continuous damage and excessive repair of alveolar epithelial cells, the …

Smad4-dependent regulation of type I collagen expression in the muscle of grass carp fed with faba bean

E Yu, L Ma, H Ji, Z Li, G Wang, J Xie, D Yu, G Kaneko… - Gene, 2019 - Elsevier
Smad4 is the key regulator in the transforming growth factor β1 (TGF-β1)/Smads signal
pathway, and is also the crux of the regulation of type I collagen expression in mammals. In …

Idiopathic pulmonary fibrosis in BRIC countries: the cases of Brazil, Russia, India, and China

L Richeldi, AS Rubin, S Avdeev, ZF Udwadia, ZJ Xu - BMC medicine, 2015 - Springer
Idiopathic pulmonary fibrosis (IPF), the prototype of interstitial lung diseases, has the worst
prognosis and is the only interstitial lung disease for which approved pharmacological …

Optimization of ultrasonic-assisted extraction of oil from the seed kernels and isolation of monoterpene glycosides from the oil residue of Paeonia lactiflora Pall.

P Liu, Y Xu, X Gao, X Zhu, M Du, Y Wang… - Industrial Crops and …, 2017 - Elsevier
Ultrasonic-assisted extraction of oil from Paeonia lactiflora Pall. seeds with hexane as the
solvent was studied, and the chemical composition of the oil was analyzed by gas …

Danshensu alleviates bleomycin-induced pulmonary fibrosis by inhibiting lung fibroblast-to-myofibroblast transition via the MEK/ERK signaling pathway

H Liu, X Zhang, Y Shao, X Lin, F Dong, X Liu - Bioengineered, 2021 - Taylor & Francis
Pulmonary fibrosis (PF) is a chronic pulmonary interstitial disease, and its pathological
process is closely related to fibroblast–myofibroblast differentiation. Danshensu (DSS) has …

The gut-lung axis: gut microbiota changes associated with pulmonary fibrosis in mouse models induced by bleomycin

Y Quan, Z Yin, S Chen, J Lang, L Han, J Yi… - Frontiers in …, 2022 - frontiersin.org
The main objective of this study was to investigate the alterations in the gut microbiota (GM)
of pulmonary fibrosis (PF) mice induced by bleomycin (BLM) with its underlying …

[HTML][HTML] Effects of plant extracts and bioactive compounds on attenuation of bleomycin-induced pulmonary fibrosis

S Hosseini, M Imenshahidi, H Hosseinzadeh… - Biomedicine & …, 2018 - Elsevier
Introduction Bleomycin (BLM) is a chemotherapeutic agent that is used in the management
of some human cancers such as lymphomas and squamous cell carcinomas. The major …

Calycosin attenuates pulmonary fibrosis by the epithelial-mesenchymal transition repression upon inhibiting the AKT/GSK3β/β-catenin signaling pathway

X Liu, Y Shao, X Zhang, X Ji, M Xie, H Liu - Acta Histochemica, 2021 - Elsevier
The precise etiology and pathogenesis of idiopathic pulmonary fibrosis are not completely
understood, and no satisfactory treatment exists. This work aimed to examine the effects of …

Nigella sativa, a traditional Tunisian herbal medicine, attenuates bleomycin-induced pulmonary fibrosis in a rat model

A Abidi, A Robbe, N Kourda, SB Khamsa… - Biomedicine & …, 2017 - Elsevier
The present study investigated the effects of Nigella sativa oil (NSO) on bleomycin (BLM)-
induced lung fibrosis in rats. The rat model of pulmonary fibrosis (PF) was established by …