Adverse drug reaction is defined by the World Health Organization as any response to a
drug that is noxious and unintended and occurs at a dose normally used in man. Older …

Introduction: The difficulty of understanding and diagnosing drug-induced liver injury (DILI)
has led to proliferation of serum and genetic biomarkers. Many applications of these …

We report a case of a man with COVID-19 who developed acute hepatotoxicity related to
remdesivir with probable interaction of P-glycoprotein (P-gp) inhibitors. Until further details …

Berberine (BBR) exerts documented protection against neurodegenerative disorders.
However, data on the effect of nano-encapsulation on the neuroprotective effect of BBR are …

Abstract Polysorbate 80 for injection (TW80) is a common excipient used for injection whose
macromolecular impurities, including those that cause anaphylactoid reactions, are …

Acute hepatitis is a very rare, but potentially fatal, adverse effect of intravenous amiodarone.
We present a case of an 88-year-old man with history of ischemic dilated cardiomyopathy …

Antiarrhythmic drugs are commonly prescribed cardiac drugs. Due to their receptor mimicry
with several of the gastrointestinal tract receptors, they can frequently lead to gastrointestinal …

Abstract Introduction Potentially harmful excipients (PHEs) for children have been reported
and the need for information collection has been advocated. However, studies on the actual …

DISCUSSION Despite its ubiquitous and clinically important role as a central antiarrhythmic
agent, amiodarone's significant toxicity and side effect profile represent a considerable …

PURPOSE We aimed to improve our understanding of amiodarone and its ocular adverse
effects by performing a systematic review and meta-analysis of published case reports …