Ebola virus disease

ST Jacob, I Crozier, WA Fischer, A Hewlett… - Nature reviews Disease …, 2020 - nature.com
Ebola virus disease (EVD) is a severe and frequently lethal disease caused by Ebola virus
(EBOV). EVD outbreaks typically start from a single case of probable zoonotic transmission …

Tracking virus outbreaks in the twenty-first century

ND Grubaugh, JT Ladner, P Lemey, OG Pybus… - Nature …, 2019 - nature.com
Emerging viruses have the potential to impose substantial mortality, morbidity and economic
burdens on human populations. Tracking the spread of infectious diseases to assist in their …

Spread of a SARS-CoV-2 variant through Europe in the summer of 2020

EB Hodcroft, M Zuber, S Nadeau, TG Vaughan… - Nature, 2021 - nature.com
Following its emergence in late 2019, the spread of SARS-CoV-2, has been tracked by
phylogenetic analysis of viral genome sequences in unprecedented detail,–. Although the …

[HTML][HTML] The impact of mutations in SARS-CoV-2 spike on viral infectivity and antigenicity

Q Li, J Wu, J Nie, L Zhang, H Hao, S Liu, C Zhao… - Cell, 2020 - cell.com
The spike protein of SARS-CoV-2 has been undergoing mutations and is highly
glycosylated. It is critically important to investigate the biological significance of these …

[HTML][HTML] Structural and functional analysis of the D614G SARS-CoV-2 spike protein variant

L Yurkovetskiy, X Wang, KE Pascal, C Tomkins-Tinch… - Cell, 2020 - cell.com
Summary The SARS-CoV-2 spike (S) protein variant D614G supplanted the ancestral virus
worldwide, reaching near fixation in a matter of months. Here we show that D614G was …

Characterization of spike glycoprotein of SARS-CoV-2 on virus entry and its immune cross-reactivity with SARS-CoV

X Ou, Y Liu, X Lei, P Li, D Mi, L Ren, L Guo… - Nature …, 2020 - nature.com
Abstract Since 2002, beta coronaviruses (CoV) have caused three zoonotic outbreaks,
SARS-CoV in 2002–2003, MERS-CoV in 2012, and the newly emerged SARS-CoV-2 in late …

Resurgence of Ebola virus in 2021 in Guinea suggests a new paradigm for outbreaks

AK Keita, FR Koundouno, M Faye, A Düx, J Hinzmann… - Nature, 2021 - nature.com
Seven years after the declaration of the first epidemic of Ebola virus disease in Guinea, the
country faced a new outbreak—between 14 February and 19 June 2021—near the …

SARS-CoV-2 neutralizing antibodies: Longevity, breadth, and evasion by emerging viral variants

F Tea, A Ospina Stella, A Aggarwal… - PLoS …, 2021 - journals.plos.org
The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) antibody
neutralization response and its evasion by emerging viral variants and variant of concern …

Molecular architecture of early dissemination and massive second wave of the SARS-CoV-2 virus in a major metropolitan area

SW Long, RJ Olsen, PA Christensen, DW Bernard… - MBio, 2020 - Am Soc Microbiol
We sequenced the genomes of 5,085 severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) strains causing two coronavirus disease 2019 (COVID-19) disease waves in …

[HTML][HTML] Mutations of SARS-CoV-2 spike protein: Implications on immune evasion and vaccine-induced immunity

HM Mengist, AJK Kombe, D Mekonnen, A Abebaw… - Seminars in …, 2021 - Elsevier
Responsible for more than 4.9 million deaths so far, COVID-19, caused by SARS-CoV-2, is
instigating devastating effects on the global health care system whose impacts could be …