[HTML][HTML] Delta-5-desaturase: A novel therapeutic target for cancer management

L Pang, H Shah, Y Xu, S Qian - Translational oncology, 2021 - Elsevier
Abstract Delta-5 desaturase (D5D) is a rate-limiting enzyme that introduces double-bonds to
the delta-5 position of the n-3 and n-6 polyunsaturated fatty acid chain. Since fatty acid …

COX‐2 in lung cancer: Mechanisms, development, and targeted therapies

X Liu, J Zhang, W Sun, J Cao… - Chronic Diseases and …, 2024 - Wiley Online Library
Lung cancer (LC) is the leading cause of cancer‐related death worldwide, with non‐small
cell lung cancer (NSCLC) comprising 85% of all cases. COX‐2, an enzyme induced …

Iminodibenzyl induced redirected COX-2 activity inhibits breast cancer progression

H Shah, L Pang, S Qian, V Sathish - NPJ breast cancer, 2021 - nature.com
Abstract Knocking down delta-5-desaturase (D5D) by siRNA or shRNA is a promising
strategy to achieve 8-hydroxyoctanoic acid (8-HOA) production for cancer inhibition …

Synthesis and Anticancer Activity of 5-[(1-Aryl-1H-1,2,3-triazol-4-yl)methyl]-10,11-dihydro-5H-dibenzo[b,f]azepines

K Sadanandam, P Pinnoju, M Sarasija - Russian Journal of Organic …, 2024 - Springer
Abstract A novel series of 5-[(1-aryl-1 H-1, 2, 3-triazol-4-yl) methyl]-10, 11-dihydro-5 H-
dibenzo [b, f] azepine derivatives were synthesized by employing click chemistry approach …

Targeted Three-Way-Junction RNA Nanoparticle Reprogrammed Cyclooxygenase-2 Catalyzed Dihomo-ϒ-Linolenic Acid Peroxidation Pattern in Lung Cancer

L Pang - 2021 - search.proquest.com
As the second most common cancer and the first leading cause of cancer deaths, lung
cancer attracts much research attention. Since cyclooxygenase-2 (COX-2) is overexpressing …

[PDF][PDF] Effects of interstitial fluid flow and cell compression in FAK and SRC activities in chondrocytes

E Cho - 2013 - scholarworks.iupui.edu
Articular cartilage is subjected to dynamic mechanical loading during normal daily activities.
This complex mechanical loading, including cell deformation and interstitial fluid flow, affects …

[引用][C] The effects of diet on human redox state.

DR Crawford, YJ Surh - Free Radical Biology & Medicine, 2021 - europepmc.org
The effects of diet on human redox state. - Abstract - Europe PMC Sign in | Create an account
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