Major depressive disorder is a highly debilitating psychiatric disorder involving the
dysfunction of different cell types in the brain. Microglia are the predominant resident …

Since the Coronavirus disease 2019 (COVID-19) pandemic, caused by Severe Acute
Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) was announced, we had an …

Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) is a new pandemic infectious disease that originated in China …

Mood disorders are associated with elevated inflammation, and the reduction of symptoms
after multiple treatments is often accompanied by pro-inflammation restoration. A variety of …

Abstract The Coronavirus Disease 2019 (COVID-19) represents a severe multiorgan
pathology which, besides cardio-respiratory manifestations, affects the function of the central …

Early life adversity (ELA) is a major risk factor for mental illness, but the neurobiological
mechanisms by which ELA increases the risk for future psychopathology are still poorly …

The synaptic hypothesis of schizophrenia has been highly influential. However, new
approaches mean there has been a step-change in the evidence available, and some tenets …

Inflammation is a natural defence response of the immune system against environmental
insult, stress and injury, but hyper-and hypo-inflammatory responses can trigger diseases …

Depression represents a global mental health concern, and disproportionally affects women
as they are twice more likely to be diagnosed than men. In this review, we provide a …

While modernization has dramatically increased lifespan, it has also witnessed the nature of
stress has changed dramatically. Chronic stress result failures of homeostasis and thus lead …