[HTML][HTML] NMR-based metabolic profiles of intact zebrafish embryos exposed to aflatoxin B1 recapitulates hepatotoxicity and supports possible neurotoxicity

Z Zuberi, MNH Eeza, J Matysik, JP Berry, A Alia - Toxins, 2019 - mdpi.com
Aflatoxin B1 (AFB1) is a widespread contaminant of grains and other agricultural crops and
is globally associated with both acute toxicity and carcinogenicity. In the present study, we …

Protective effects of curcumin against aflatoxicosis: A comprehensive review

M Mohajeri, B Behnam, AFG Cicero… - Journal of cellular …, 2018 - Wiley Online Library
Aflatoxicosis is a deleterious medical condition that results from aflatoxins (AFs) or
ochratoxins (OTs). Contamination with these toxins exerts detrimental effects on the liver …

[HTML][HTML] May phytophenolics alleviate aflatoxins-induced health challenges? A holistic insight on current landscape and future prospects

H Rasouli, FD Nayeri, R Khodarahmi - Frontiers in nutrition, 2022 - frontiersin.org
The future GCC-connected environmental risk factors expedited the progression of nCDs.
Indeed, the emergence of AFs is becoming a global food security concern. AFs are lethal …

Selenium Alleviates Aflatoxin B1-Induced Immune Toxicity through Improving Glutathione Peroxidase 1 and Selenoprotein S Expression in Primary Porcine …

S Hao, J Hu, S Song, D Huang, H Xu… - Journal of agricultural …, 2016 - ACS Publications
Selenium (Se) is generally known as an essential micronutrient and antioxidant for humans
and animals. Aflatoxin B1 (AFB1) is a frequent contaminant of food and feed, causing …

Aflatoxin B1 Induces Gut-Inflammation-Associated Fecal Lipidome Changes in F344 Rats

J Zhou, L Tang, JS Wang - Toxicological Sciences, 2021 - academic.oup.com
Abstract Aflatoxin B1 (AFB1) induced intestinal epithelial damage in rodent models, which
indicates that long-term exposure to AFB1 may cause chronic gut disorders. In this study, we …

The Ameliorative Role of Lico A on Aflatoxin B1-Triggered Hepatotoxicity Partially by Activating Nrf2 Signal Pathway

H Lv, J Liu, Y He, S Xia, C Qiao… - Journal of Agricultural and …, 2024 - ACS Publications
Aflatoxin B1 (AFB1) is one of the most harmful and toxic mycotoxins in foods and feeds,
posing a serious health risk to both humans and animals, especially its hepatotoxicity …

[HTML][HTML] Current status and future opportunities of omics tools in mycotoxin research

M Eshelli, MM Qader, EJ Jambi, AS Hursthouse… - Toxins, 2018 - mdpi.com
Mycotoxins are toxic secondary metabolites of low molecular weight produced by
filamentous fungi, such as Aspergillus, Fusarium, and Penicillium spp. Mycotoxins are …

[HTML][HTML] Embryonic exposure to low concentrations of aflatoxin B1 triggers global transcriptomic changes, defective yolk lipid mobilization, abnormal gastrointestinal …

B Ivanovics, G Gazsi, M Reining, I Berta… - Journal of Hazardous …, 2021 - Elsevier
Aflatoxin B1-contaminated feeds and foods induce various health problems in domesticated
animals and humans, including tumor development and hepatotoxicity. Aflatoxin B1 also has …

[HTML][HTML] Ochratoxin A induced early hepatotoxicity: new mechanistic insights from microRNA, mRNA and proteomic profiling studies

X Qi, X Yang, S Chen, X He, H Dweep, M Guo… - Scientific reports, 2014 - nature.com
The mycotoxin ochratoxin A (OTA) is found widely in agricultural commodities. OTA can
induce various toxicities. In this study, rats were gavaged with OTA for different weeks. Then …

Transcriptomic and proteomic profiling reveals the intestinal immunotoxicity induced by aflatoxin M1 and ochratoxin A

Y Gao, Q Ye, X Bao, X Huang, J Wang, N Zheng - Toxicon, 2020 - Elsevier
Mycotoxins-contaminated milk could threaten human health; therefore, it is necessary to
demonstrate the toxicological effect of mycotoxins in milk. Most recently, researchers have …